Browsing by Author "Ekinci, Deniz"

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Inhibition of human carbonic anhydrase isozymes I, II and VI with a series of bisphenol, methoxy and bromophenol compounds

Balaydın, Halis Türker; Durağı, Serdar; Ekinci, Deniz; Şentürk, Murat; Göksoy, Süleyman; Menzek, Abdullah (Taylor & Francis Inc, 2012)

Carbonic anhydrase inhibitors (CAI) are valuable molecules as they have several therapeutic applications, including anti-glaucoma activity. In this study, inhibition of three human carbonic anhydrase (hCA, EC 4.2.1.1) ...
Synthesis and biological evaluation of novel bromophenol derivatives as carbonic anhydrase inhibitors

Akbaba, Yusuf; Balaydın, Halis Türker; Menzek, Abdullah; Göksu, Süleyman; Şahin, Ertan; Ekinci, Deniz (Wiley-V C H Verlag Gmbh, 2013)

Here, we provide an alternative synthesis of the natural bromophenol 3,4-dibromo-5-(2,3-dibromo-4,5-dihydroxybenzyl)-6-(ethoxymethyl) benzene-1,2-diol (3) and the first synthesis of (4,5-dihydroxy-2methylphenyl)( ...
Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols including natural products

Balaydın, Halis Türker; Soyut, Hakan; Ekinci, Deniz; Göksu, Süleyman; Beydemir, Şükrü; Menzek, Abdullah; Şahin, Ertan (Taylor and Francis Ltd., 2012)

(2-Bromo-3,4-dimethoxyphenyl) (3,4-dimethoxyphenyl) methanone (10) and its derivatives with Br, one dibromide and isomeric three tribromides, were synthesized. Demethylation of these compounds afforded a series of new ...