Browsing by Author "Metintaş, Muzaffer"

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Determination of the relationship between rs4986790 and rs4986791 variants of TLR4 gene and lung cancer

Hülyam, Kurt; Özbayer, Cansu; Bayramoğlu, Ayşegül; Güneş, Hasan Veysi; Degirmenci, İrfan; Öner, Kevser Setenay; Metintaş, Muzaffer (Springer New York LLC, 2016)

Chronic inflammation triggers DNA damage and oncogenic mutations and causes tumor formation and tumor progression. One of the important components of the inflammatory response is Toll-like receptor (TLR) family. The objective ...
Plasminogen activator inhibitor-1 and susceptibility to lung cancer: a population genetics perspective

Bayramoğlu, Ayşegül; Güneş, Hasan Veysi; Metintaş, Muzaffer; Degirmenci, İrfan; Güler, Halil İbrahim; Üstüner, Cengiz; Musmul, Ahmet (Mary Ann Liebert Inc., 2014)

Aim: The aim of this study was to investigate the polymorphism frequency of plasminogen activator inhibitor-1 (PAI-1) (rs1799889) 4G/5G in patients with lung cancer. Methods: In this study, 286 genomic DNAs (154 lung cancer ...
The role of NOD1/CARD4 and NOD2/CARD15 genetic variations in lung cancer risk

Özbayer, Cansu; Kurt, Hülyam; Bayramoğlu, Ayşegül; Güneş, Hasan Veysi; Metintaş, Muzaffer; Değirmenci, İrfan; Öner, Kevser Setenay (Springer Basel Ag, 2015)

Background and aim NOD1/CARD4 and NOD2/CARD15 are members of the Nod-like receptor (NLR) family, and they contain a caspase recruitment domain (CARD). NLRs are located in the cytosol where they bind bacterial and viral ...