Yazar "Ata, Oğuz" için Sağlık Hizmetleri Meslek Yüksekokulu Yayın Koleksiyonu listeleme
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Evaluation of the potency of FDA-approved drugs on wild type and mutant SARS-CoV-2 helicase (Nsp13)
Uğurel, Osman Mutluhan; Mutlu, Özal; Sarıyer, Emrah; Koçer, Sinem; Uğurel, Erennur; İnci, Tuğba Gül; Ata, Oğuz; Turgut Balık, Dilek (Elsevier BV, 2020)SARS-CoV-2 has caused COVID-19 outbreak with nearly 2 M infected people and over 100K death worldwide, until middle of April 2020. There is no confirmed drug for the treatment of COVID-19 yet. As the disease spread fast ... -
Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: anin silicostructure-based approach
Mutlu, Özal; Uğurel, Osman Mutluhan; Sarıyer, Emrah; Ata, Oğuz; İnci, Tuğba Gül; Uğurel, Erennur (Taylor & Francis Inc, 2020)In this study, the Nsp12-Nsp8 complex of SARS-CoV-2 was targeted with structure-based and computer-aided drug design approach because of its vital role in viral replication. Sequence analysis of RNA-dependent RNA polymerase ...