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Type 2 diabetes mellitus and diabetic nephropathy with angiotensin ii type 1 receptor gene variants: A case control study in a Turkish population
(Kuwait Medical Association, 2020)
Objective: This study was performed to determine the polymorphism frequencies of the Angiotensin II type 1 receptor (AT1) A1166C, and to examine the role of this polymorphism in type-2 diabetes (T2DM) and diabetic nephropathy ...
Gallic acid reduces experimental colitis in rats by downregulation of cathepsin and oxidative stress
(Erciyes Univ Sch Medicine, 2020)
Objective: Ulcerative colitis (UC) is an idiopathic inflammatory bowel disease (IBD) with common, repetitive inflammation
of the colon and rectum, which is highly defined by loss of blood on colon mucosa, ulceration and ...
Carvacrol partially reverses symptoms of diabetes in STZ-induced diabetic rats
(Springer, 2014)
Little is known about the protective effects of carvacrol on the symptoms of streptozotocin induced diabetes in rats. Hence, this present study was designed to evaluate the protective effect of the strong antioxidant, ...
The role of rs1799889 genetic variation in type 2 diabetes and diabetic nephropathy risk
(Erciyes Univ Sch Medicine, 2020)
AI-1 gene 4G/5G and to investigate the role of this polymorphism in T2 DM and DN development.
Materials and Methods: The genomic DNA of the 261 individuals was included in this study. The polymerase chain reaction (PCR) ...
The effects of lycopene on hepatic ischemia/reperfusion injury in rats
(Springer, 2015)
There is a very little information about the protective effect of lycopene (LYC) against hepatic ischemia-reperfusion injury. The present study was designed to examine the possible protective effect of the strong antioxidant ...
Genetic variations of Renin-angiontensin and Fibrinolytic systems and susceptibility to coronary artery disease: a population genetics perspective
([y.y.], 2020)
BACKGROUND: Genetic predisposition is an important risk factor in coronary artery disease (CAD).This study was conducted to determine the polymorphism frequencies of the plasminogen activator inhibitor-1(PAI-1) gene 4G/5G, ...
Lycopene partially reverses symptoms of diabetes in rats with streptozotocin-induced diabetes
(Mary Ann Liebert Inc., 2013)
In the present study, we describe the effects of lycopene on the symptoms of streptozotocin (STZ)–induced
diabetes in rats. Lycopene at the dose of 2.5 mg/kg body weight (bw) per day was orally administered to STZ-induced ...
Preventive role of gallic acid on hepatic ischemia and reperfusion injury in rats
(Springer, 2015)
There is little information about the hepatoprotective effects of gallic acid against ischemia-reperfusion (I/R) damage. Animals were subjected to I/R. Gallic acid at doses of 50 and 100 mg/kg body weight (bw) were injected ...
The effect of Echinacea on kidney and liver after experimental renal ischemia/reperfusion injury in the rats
(Academic Journals, 2011)
The aim of the study is to investigate the effect of Echinacea on kidney and liver against oxidative stress during renal ischemia-reperfusion (I/R) injury, by determining biochemical parameters and evaluating histological ...
The hepatoprotective effects of Hypericum perforatum L. on hepatic ischemia/reperfusion injury in rats
(Springer, 2014)
Little is known about the effective role of Hypericum perforatum on hepatic ischemia-reperfusion (I/R) injury in rats. Hence, albino rats were subjected to 45 min of hepatic ischemia followed by 60 min of reperfusion period. ...
