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Comparison of verona integron-borne metallo-β-lactamase (VIM) variants reveals differences in stability and inhibition profiles
(Amer Soc Microbiology, 2015)
Metallo-beta-lactamases (MBLs) are of increasing clinical significance; the development of clinically useful MBL inhibitors is challenged by the rapid evolution of variant MBLs. The Verona integron-borne metallo-beta-lactamase ...
The effects of lycopene on hepatic ischemia/reperfusion injury in rats
(Springer, 2015)
There is a very little information about the protective effect of lycopene (LYC) against hepatic ischemia-reperfusion injury. The present study was designed to examine the possible protective effect of the strong antioxidant ...
Preventive role of gallic acid on hepatic ischemia and reperfusion injury in rats
(Springer, 2015)
There is little information about the hepatoprotective effects of gallic acid against ischemia-reperfusion (I/R) damage. Animals were subjected to I/R. Gallic acid at doses of 50 and 100 mg/kg body weight (bw) were injected ...
Thermus anatoliensis sp nov., a thermophilic bacterium from geothermal waters of Buharkent, Turkey
(Wiley, 2015)
A Gram-stain-negative, lack of motility, catalase- and oxidase- positive bacterium (strain MT1(T)) was isolated from Buharkent hot spring in Aydin, Turkey. Its taxonomy was investigated using a polyphasic approach. The ...
Distribution of beta-lactamase genes among carbapenem-resistant klebsiella pneumoniae strains isolated from patients in Turkey
(Korean Society for Laboratory Medicine, 2015)
Background: The emergence of carbapenem-resistant Klebsiella pneumoniae poses a serious problem to antibiotic management. We investigated the beta-lactamases in a group of carbapenem-resistant K. pneumoniae clinical isolates ...
Histopathological findings and apoptosis caused by E. coli in layer birds
(Univ Agriculture, 2015)
In this study, our aim was to evaluate lesions seen in the tissues in terms of histopathology and to investigate the apoptotic cells seen in the tissues when E. coli outbreak occurred in a poultry farm. A total of 48 Lohmann ...
Angiotensin II type 1 receptor (AT1) gene A1166C is associated with the risk of hypertension
(Mary Ann Liebert Inc., 2015)
Aim: This study was performed on primary hypertension patients in a Turkish population to determine the frequency of the A1166C polymorphism in the angiotensin II type 1 receptor (AT1) gene and to examine the role of this ...
Investigation of relationship between IL-6 gene variants and hypertension in Turkish population
(Springer, 2015)
Hypertension (HT) is a common and life threating health problem worldwide leading to stroke, heart attack and renal failure. It is characterized by elevated blood pressure forced heart load. Human interleukin-6 (IL-6) and ...
Is there any genetic predisposition of MMP-9 gene C1562T and MTHFR gene C677T polymorphisms with essential hypertension?
(Springer, 2015)
The current study was conducted to determine whether there is a relation between hypertension and two different polymorphisms, including C1562T of the Matrix metalloproteinase-9 (MMP-9) gene and C677T of the methylenetet ...
The role of NOD1/CARD4 and NOD2/CARD15 genetic variations in lung cancer risk
(Springer Basel Ag, 2015)
Background and aim NOD1/CARD4 and NOD2/CARD15 are members of the Nod-like receptor (NLR) family, and they contain a caspase recruitment domain (CARD). NLRs are located in the cytosol where they bind bacterial and viral ...
