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Microwave-assisted synthesis of some hybrid molecules derived from morpholine and investigation of their antimicrobial activities

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info:eu-repo/semantics/closedAccess

Date

2017

Author

Cebeci, Yıldız Uygun
Özdemir, Serap Başoğlu
Ceylan, Şule
Bayrak, Hacer
Demirbaş, Ahmet
Alpay Karaoğlu, Şengül
Demirbaş, Neslihan

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Citation

Cebeci, Y. U., Ozdemir, S. B., Demirbas, A., Demirbas, N., Ceylan, S., Bayrak, H., & Alpay-Karaoglu, S.. (2017). Microwave-Assisted Synthesis of Some Hybrid Molecules Derived from Morpholine and Investigation of Their Antimicrobial Activities. ChemistrySelect, 2(35), 11402–11407. https://doi.org/10.1002/slct.201702097

Abstract

2H-1,2,4-triazol-3(4H)-one compound was obtained starting from 4-(2-fluoro-4-nitrophenyl)morpholine via several steps. Then, these compounds were converted to the corresponding fluoroquinolone hybrids via one pot three component Mannich reaction. Moreover, the synthesis of eleven compounds, which can be considered as conazole analogues, was performed starting from 1,2,4-triazole-3-one compounds via three steps by either conventional or microwave mediated conditions. The effect of different solvents and microwave power on microwave prompted reactions was examined as well.

Source

ChemistrySelect

Volume

2

Issue

35

URI

https://hdl.handle.net/11494/1974

Collections

  • Artvin MYO Koleksiyonu - Makaleler [74]
  • Scopus İndeksli Yayınlar Koleksiyonu [525]
  • WoS İndeksli Yayınlar Koleksiyonu [685]



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