dc.contributor.author | Dokumacıoğlu, Eda | |
dc.contributor.author | İskender, Hatice | |
dc.contributor.author | Şahin, Arzu | |
dc.contributor.author | Ertürk, Yurdakul Emine | |
dc.contributor.author | Kaynar, Özgür | |
dc.date.accessioned | 2020-06-22T08:35:26Z | |
dc.date.available | 2020-06-22T08:35:26Z | |
dc.date.issued | 2020 | en_US |
dc.identifier.citation | Dokumacıoğlu, E., İskender, H., Şahin, A., Ertürk, E. Y., & Kaynar, O. (2020). Serum levels of nesfatin-1 and irisin in obese children. European Cytokine Network, 31(1), 39-43. doi: 10.1684/ecn.2020.0444. | en_US |
dc.identifier.uri | https://hdl.handle.net/11494/2113 | |
dc.description | This work was supported by Coordinator of Scientific Research Projects at Artvin Çoruh University. | en_US |
dc.description.abstract | Background: Along with the developing technology in the modern age, physical activity had decreased considerably in children and adolescents alike with a concomittant and rapid increase in the prevalence of childhood obsesity. The purpose of the present study is to measure the levels of serum nesfatin-1 and irisin in obese children. Methods: The present study was carried out with a total of 62 children, including 32 obese children diagnosed between June 2017 and October 2017 and 30 healthy children. Serum nesfatin-1, irisin, SOD,MDA, fasting blood glucose, total cholesterol (TC), triglyceride (TG), HDL-C, LDL-C, aspartate amino transferase (AST), alanine amino transferase (ALT)), blood urea nitrogen (BUN), C-reactive protein (CRP), calcium (Ca), sodium (Na), potassium (P), chromium (Cr), ferritin, and vitamin B12 data were collected for each patient. Results: In our study, mean nesfatin-1 and SOD values of the obesity group were lower than those of the control group (p <0.05, p <0.001), whereas irisin and MDA values were higher than those of the control group (p <0.001). Conclusion: Childhood obesity is still a significant global problem, despite increased social awareness and numerous preventive healthcare interventions. We believe that all the prospective studies to be carried out to evaluate the relationship between obesity-irisin-nesfatin-1 triad, will make positive contributions to treatment of obesity. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | John Libbey Eurotext | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Irisin | en_US |
dc.subject | Nesfatin-1 | en_US |
dc.subject | Obesity | en_US |
dc.subject | Oxidative stress | en_US |
dc.title | Serum levels of nesfatin-1 and irisin in obese children | en_US |
dc.type | article | en_US |
dc.relation.journal | European Cytokine Network | en_US |
dc.department | AÇÜ, Sağlık Bilimleri Fakültesi | en_US |
dc.authorid | 0000-0002-2223-1331 | en_US |
dc.identifier.volume | 31 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 39 | en_US |
dc.identifier.endpage | 43 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1684/ecn.2020.0444 | en_US |
dc.contributor.institutionauthor | Dokumacıoğlu, Eda | en_US |
dc.contributor.institutionauthor | İskender, Hatice | |