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dc.contributor.authorUslu, Sema
dc.contributor.authorÖzçelik, Eda
dc.contributor.authorKebapçı, Nur
dc.contributor.authorTemel, Halide Edip
dc.contributor.authorDemirci, Fatih
dc.contributor.authorErgün, Bülent
dc.contributor.authorDemirüstü, Canan
dc.date.accessioned2020-11-13T07:18:19Z
dc.date.available2020-11-13T07:18:19Z
dc.date.issued2016en_US
dc.identifier.citationUslu, S., Özçelik, E., Kebapçı, N., Temel, H. E., Demirci, F., Ergün, B., & Demirüstü, C. (2016). Effects of serum uric acid levels on the arginase pathway in women with metabolic syndrome. Irish Journal of Medical Science. 185(1), 259-263.en_US
dc.identifier.urihttps://hdl.handle.net/11494/2452
dc.description.abstractAbstract Background Elevated serum uric acid levels and increased arginase activity are risk factors for cardiovascular diseases (CVD). The aim of the present study was to investigate effects of serum uric acid levels on the arginase pathway in women with metabolic syndrome (MetS). Methods Serum arginase activity, and nitrite and uric acid levels were measured in 48 women with MetS and in 20 healthy controls. The correlation of these parameters with components of MetS was also evaluated. Results Our data show statistically higher arginase activity and uric acid levels but lower nitrite levels in women with MetS compared to controls. Serum uric acid levels were negatively correlated with HDL cholesterol, nitrite levels and positively with Body Mass Index, waist to hip ratio, triglyceride and total cholesterol levels, systolic blood pressure, Homeostasis Model Assessment-Insulin Resistance-Index, serum arginase activity, and LDL-cholesterol levels in women with MetS. Conclusion Results of the present study suggest that serum uric acid levels may contribute to the pathogenesis of MetS through a process mediated by arginase pathway, and serum arginase activity and nitrite and uric acid levels can be used as indicators of CVD in women with MetS.en_US
dc.language.isoengen_US
dc.publisherSpringer London LTDen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArginase pathwayen_US
dc.subjectMetabolic syndromeen_US
dc.subjectSerum uric acid levelsen_US
dc.titleEffects of serum uric acid levels on the arginase pathway in women with metabolic syndromeen_US
dc.typearticleen_US
dc.relation.journalIrish Journal of Medical Science.en_US
dc.departmentAÇÜ, Sağlık Bilimleri Fakültesien_US
dc.identifier.volume185en_US
dc.identifier.issue1en_US
dc.identifier.startpage259en_US
dc.identifier.endpage263en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1007/s11845-015-1347-9en_US
dc.contributor.institutionauthor[0-Belirlenecek]en_US


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