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Toplam kayıt 20, listelenen: 1-10
Synthesis and antimicrobial activities of hybrid heterocyclic molecules based on 1-(4-fluorophenyl) piperazine skeleton
(Bentham Science Publishers, 2017)
Background: The amine (2) was prepared starting from 1-(4-fluorophenyl) piperazine via two steps, and then converted to the corresponding hydrazide (4). The reaction of hydrazide (4) with carbon disulfide generated the ...
Microwave-assisted synthesis of some hybrid molecules derived from morpholine and investigation of their antimicrobial activities
(Wiley-VCH Verlag GmbH, 2017)
2H-1,2,4-triazol-3(4H)-one compound was obtained starting from 4-(2-fluoro-4-nitrophenyl)morpholine via several steps. Then, these compounds were converted to the corresponding fluoroquinolone hybrids via one pot three ...
Antimicrobial, antioxidant and antiproliferative activities of novel quinolones
(Wiley-VCH GmbH, 2020)
The compound (2) formed by esterification of dimethyl morpholine (1) was converted to acetohydrazide (3). Subsequently Schiff bases (4 a-d) and carboxy(thio)amide derivatives (5 a-e) were synthesized. Then 1,2,4-triazole ...
Microwave-assisted synthesis of novel mannich base and conazole derivatives containing biologically active pharmacological groups
(Bentham Science Publishers, 2021)
Background: The aim of this study was to synthesize new Mannich bases and conazol derivatives with biological activity by the microwave-assisted method. Introduction: 1,2,4-Triazole-3-one (3) acquired from tryptamine was ...
Microwave-assisted and conventional synthesis of novel antimicrobial 1,2,4-triazole derivatives containing nalidixic acid skeleton
(Walter De Gruyter Gmbh, 2016)
Carbothioamides 4a,b, obtained from nalidixic acid, were converted to the corresponding 1,3-thiazolidine derivatives 5a,b by cyclocondensation with 2-bromo-1-(4-chlorophenyl)ethanone. Treatment of 4a,b with base afforded ...
Synthesis and biological evaluation of new Mannich and Schiff bases containing 1,2,4-triazole and 1,3,4-oxadiazole nucleus
(Springer, 2016)
5-(Pyridine-3-yl)-1, 3, 4-oxadiazole-2-thiole 2,
obtaining starting from nicotinic acid hydrazide were converted to the corresponding Mannich bases (3a–c) by the
reaction with several heterocyclic amines in the presence ...
Determination of antioxidant and antimicrobial activity of sweetgum (Liquidambar orientalis) leaf, a medicinal plant
(Assoc Brasil Polimeros, 2021)
In the study, sweetgum tree (Liquidambar orientalis), which is an endemic species that grows in Mugla, Koycegiz and is applied for medicinal purposes among the public, its leaves was examined. The antioxidant ability of ...
Novel microwave assisted synthesis and antimicrobial activity of new quinolone-hybrids
(Bentham Science Publ Ltd, 2016)
Background: Carbo(thio)amid derivatives 4a, 4b were obtained starting from nalidixic acid in three steps. The acidic treatment of compound 4a generated the corresponding 1,3,4-oxadiazole (5), while the compound 4a gave ...
Synthesis and antimicrobial, antiproliferative evaluation of novel quinolone and conazole analogues via conventional and microwave techniques
(John Wiley and Sons Inc, 2021)
1,2,4-Triazole-3-one (3), acquired from cinnamaldehyde was converted to the corresponding carbox(thio)amides via several steps (6 a–c). Their reaction with sodium hydroxide gave the 1,2,4-triazole derivatives (7 a–c). ...
Synthesis of some new hybride molecules containing several azole moieties and investigation of their biological activities
(Maik Nauka/Interperiodica/Springer, 2014)
1,2,4-Triazole-3-one prepared from tryptamine was converted to the corresponding carbothioamides by several steps. Their treatment with ethyl bromoacetate or 4-chlorophenacyl bromide produced the corresponding 5-oxo-1,3- ...