dc.contributor.author | Özdemir, Serap Başoğlu | |
dc.contributor.author | Cebeci, Yıldız Uygun | |
dc.contributor.author | Bayrak, Hacer | |
dc.contributor.author | Mermer, Arif | |
dc.contributor.author | Demirbaş, Ahmet | |
dc.contributor.author | Karaoğlu, Sengül Alpay | |
dc.contributor.author | Demirbaş, Neslihan | |
dc.contributor.author | Ceylan, Şule | |
dc.date.accessioned | 2021-04-08T11:37:16Z | |
dc.date.available | 2021-04-08T11:37:16Z | |
dc.date.issued | 2017 | en_US |
dc.identifier.citation | Özdemir, S. B., Cebeci, Y. U., Bayrak, H., Mermer, A., Ceylan, S., Demirbaş, A., ... & Demirbaş, N. (2017). Synthesis and antimicrobial activity of new piperazine-based heterocyclic compounds. Heterocyclic Communications, 23(1), 43-54. | en_US |
dc.identifier.uri | https://doi.org/10.1515/hc-2016-0125 | |
dc.identifier.uri | https://hdl.handle.net/11494/2971 | |
dc.description | Karadeniz Technical University, BAP, Turkey (Ref. No. 8623) is gratefully acknowledged. | en_US |
dc.description.abstract | The hydrazide 5, that was obtained from -1-(4-fluorophenyl) piperazine (1), was converted to the cor-responding carbothioamides 6a-c by the reaction with alkyl(aryl) isothiocyanates. The synthesis of conazole analogs 10a-f was performed via the intermediary of triazoles 7a-c. The condensation of triazoles 7a-c with -several -heterocyclic amines in the presence of formalde-hyde afforded the corresponding N-aminoalkylated tria-zoles 11-14. The effect of different catalysts and solvents on conventional and microwave (MW)-prompted reac-tions was examined. The synthesized compounds were screened for their antimicrobial activities. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Walter De Gruyter Gmbh | en_US |
dc.relation.isversionof | 10.1515/hc-2016-0125 | en_US |
dc.relation.isversionof | 10.1515/hc-2016-0125 | |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
dc.subject | Antimicrobial activity | en_US |
dc.subject | Conazole | en_US |
dc.subject | Mannich base | en_US |
dc.subject | Microwave | en_US |
dc.subject | Piperazine | en_US |
dc.title | Synthesis and antimicrobial activity of new piperazine-based heterocyclic compounds | en_US |
dc.type | article | en_US |
dc.relation.journal | Heterocyclic Communications | en_US |
dc.identifier.volume | 23 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 43 | en_US |
dc.identifier.endpage | 54 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.relation.tubitak | 113Z181 | |
dc.contributor.institutionauthor | Ceylan, Şule | |