Browsing by Author "Sedash, Yuriy V."
5-(5-Bromo-2-hydroxy-3-methoxyphenyl)-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol Kondratiuk, Michael; Gorobets, Nikolay Yu.; Sedash, Yuriy V.; Gümüş, Mustafa Kemal; Desenko, Sergey M. (MDPI, 2016)The title compound was synthesized by multicomponent condensation of 3-amino-1,2,4-triazole, acetone and 5-bromo-2-hydroxy-3-methoxybenzaldehyde. The structure was established by H-1-NMR, C-13-NMR, IR spectroscopy and LC-MS.
A modified Biginelli reaction toward oxygen-bridged tetrahydropyrimidines fused with substituted 1,2,4-triazole ring A microwave-assisted Biginelli-like three-component condensation using salicylic aldehyde derivatives, acetone, and 5-substituted 3-amino-1,2,4-triazoles instead of the urea component results in the formation of oxygen-bridged ...
Rapid formation of chemical complexity via a modified Biginelli reaction leading to dihydrofuran-2(3H)-one spiro-derivatives of triazolo[1,5-a]pyrimidine Gümüş, Mustafa Kemal; Gorobets, Nikolay Yu.; Sedash, Yuriy V.; Shishkina, Svitlana V.; Desenko, Sergey M. (Pergamon-Elsevier Science Ltd, 2017)The regio- and stereoselective, catalyst-free multicomponent synthesis of spiro-conjugated dihydrofuran-2(3H)-one/triazolo[1,5-a]pyrimidine derivatives in good to high yields via a Biginelli approach starting from ...