Ara
Toplam kayıt 9, listelenen: 1-9
In vitro and in silico evaluation of some plant extracts and phytocompounds against multidrug-resistant Gram-negative bacteria
(Springer, 2021)
The spread of multidrug-resistant Gram-negative (MDR) bacteria is a global public health problem, as infections caused by
MDR Gram-negative bacteria are difcult to treat. New antibiotic agents need to be developed to ...
Synthesis, characterizations of aryl-substituted dithiodibenzothioate derivatives, and investigating their anti-Alzheimer's properties
(Taylor and Francis Ltd., 2021)
The main objective of the present study was to synthesize potential inhibitor/activators of AChE and hCA I-II enzymes, which are thought to be directly related to Alzheimer's disease. Dithiodibenzothioate compounds were ...
The determination of the carbonic anhydrases activators in vitro effect of mixed donor crown ethers
(Wiley, 2018)
Carbonic anhydrases (CAs) play an important function in various physiological and pathological processes. Therefore, many researchers work in this field in order to design and synthesize new drugs. Both inhibitors and ...
Investigation of in vitro and in silico effects of some novel carbazole Schiff bases on human carbonic anhydrase isoforms I and II
(Taylor & Francis Inc, 2021)
Carbonic anhydrases (CAs, EC4.2.1.1) are metalloenzymes that catalyse reversible hydration reaction of carbon dioxide to bicarbonate and protons. In recent years, there has been a great interest in inhibitors/activators ...
Milk lipid and protein profiles of abkhazian and kackar goats
(Bogor Agricultural Univ, 2018)
Fat and protein profiles of milk of Abkhazian and Kackar goats, Caucasian breeds, were compared in this study. The milk samples (n= 60) from 60 Abkhazian and Kackar goats were subjected to assessments of lipid profile using ...
Purification and characterization of dihydropyrimidine dehydrogenase enzyme from sheep liver and determination of the effects of some anaesthetic and antidepressant drugs on the enzyme activity
(Taylor & Francis Inc, 2016)
Dihydropyrimidine dehydrogenase (DPD, E.C. 1.3.1.2) was purified from sheep liver with a yield of 16.7%, purification fold of 407.5 and specific activity of 0.705 EU/mg proteins. The purification procedure consisted of ...
Secondary sulfonamides as effective lactoperoxidase inhibitors
(MDPI, 2017)
Secondary sulfonamides (4a–8h) incorporating acetoxybenzamide, triacetoxybenzamide,
hydroxybenzamide, and trihydroxybenzamide and possessing thiazole, pyrimidine, pyridine,
isoxazole and thiadiazole groups were synthesized. ...
Chemical composition, antimicrobial, and antioxidant activities of medicinal plants nutsedge and fenugreek
(North Carolina State University, 2022)
Purple nutsedge roots (Cyperus rotundus L.) and fenugreek seeds (Trigonella foenum-graecum L.) have been traditionally used as food and to treat common ailments. After extraction by solid-phase microextraction (SPME), the ...
Searching for new natural inhibitors of acetylcholinesterase enzyme
(Cumhuriyet Üniversitesi, 2022)
Acetylcholinesterase enzyme (AChE) is the enzyme that catalyzes the hydrolysis of the neurotransmitter
acetylcholine to choline. Inhibitors of this enzyme (AChE-i) are used to treat Alzheimer's, a neurodegenerative
disease. ...