ORCID "0000-0001-6373-5221" Artvin MYO Koleksiyonu Yayın Koleksiyonu için listeleme
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5-(5-Bromo-2-hydroxy-3-methoxyphenyl)-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol
Kondratiuk, Michael; Gorobets, Nikolay Yu.; Sedash, Yuriy V.; Gümüş, Mustafa Kemal; Desenko, Sergey M. (MDPI, 2016)The title compound was synthesized by multicomponent condensation of 3-amino-1,2,4-triazole, acetone and 5-bromo-2-hydroxy-3-methoxybenzaldehyde. The structure was established by H-1-NMR, C-13-NMR, IR spectroscopy and LC-MS. -
Crystal structure and Hirshfeld surface analysis of 2-{[(E)-(3-cyclo butyl-1H-1,2,4-triazol-5-yl)imino] meth yl}phenol
Gümüş, Mustafa Kemal; Şen, Fatih; Kansız, Sevgi; Dege, Necmi; Saif, Eiad (International Union of Crystallography, 2021)The title compound, C13H14N4O, was developed using the reaction of salicyl aldehyde and 3-amino-5-cyclo butyl-1,2,4-triazole in ethanol under microwave irradiation. This eco-friendly microwave-promoted method proved to be ... -
Cycloaddition of enamines with 1,4-dimethoxy-2-butyne and 2-butyne-1,4-diol mediated by titanium tetrachloride
Uludağ, Nesimi; Yarapsanlı, Yeşim; Asutay, Oktay; Gümüş, Mustafa Kemal (Taylor & Francis Inc, 2018)Enamines are versatile compounds capable of alkylations, acylations, cycloadditions and annulation cascades. They are also involved in a range of heterocycle-forming processes.1,2 The broad applicability of heterocyclic ... -
Eco-friendly synthesis of novel thiohydantoin-type sulfur-containing imidazolinone derivatives from glycine ester
Gümüş, Mustafa Kemal; Elemes, Yiannis (Springer, 2018)Imino derivatives of glycine ester were prepared from methyl glycinate by the known procedure and then they reacted with several amines under microwave irradiation without solvent that gave the corresponding glycine amides. ... -
Green formation of novel pyridinyltriazole-salicylidene schiff bases
Gümüş, Mustafa Kemal (Bentham Science Publ Ltd, 2019)Aim and Objective: In this work, water was used as solvent for the eco-friendly synthesis of imines under microwave irradiation. In the first step of the study, 5-pyridinyl-3-amino-1,2,4-triazole hydrochlorides were ... -
In Vitro Cytotoxicity of Methano[1,2,4]Triazolo-[1,5-C][1,3,5]Benzoxadiazocine Derivatives and Their Effects on Nitrite and Prostaglandin E2 (PGE2) Levels
Doğan, İnci Selin; Gümüş, Mustafa Kemal; Gorobets, Nikolay Yu; Reis, Rengin; Orak, Duygu; Sipahi, Hande; Sarı, Suat; Chebanov, Valentyn A. (Springer, 2022)Biological activity of the Biginelli type heterocycles is extremely broad and provides a suitable platform for the discovery of potent small drug-like molecules. Such activity of 3,4-dihydropyrimidin-2(1H)-one (DHPM) ... -
Synthesis, acetylcholinesterase, butyrylcholinesterase and tyrosinase inhibition, and antioxidant studies of 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetohydrazides and methyl 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetates
Gümüş, Mustafa Kemal; Doğan, İnci Selin; Barut, Burak; Özel, Arzu; Kahveci, Bahittin (Bulgarian Academy of Sciences, 2017)In this research study we intend to synthesize six new 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetohydrazides (8a-f) and six new methyl 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] ...