ORCID "0000-0001-8567-807X" Beslenme ve Diyetetik Bölümü Yayın Koleksiyonu için listeleme
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Angiotensin II type 1 receptor (AT1) gene A1166C is associated with the risk of hypertension
Bayramoğlu, Ayşegül; Kurt, Hülyam; Güneş, Hasan Veysi; Ata, Necmi; Birdane, Alparslan; Dikmen, Miris; Üstüner, Mehmet Cengiz; Çolak, Ertuğrul; Değirmenci, İrfan (Mary Ann Liebert Inc., 2015)Aim: This study was performed on primary hypertension patients in a Turkish population to determine the frequency of the A1166C polymorphism in the angiotensin II type 1 receptor (AT1) gene and to examine the role of this ... -
Carvacrol partially reverses symptoms of diabetes in STZ-induced diabetic rats
Bayramoğlu, Gökhan; Şentürk, Hakan; Bayramoğlu, Ayşegül; Uyanoğlu, Mustafa; Çolak, Suat; Özmen, Ayşe; Kolankaya, Durdane (Springer, 2014)Little is known about the protective effects of carvacrol on the symptoms of streptozotocin induced diabetes in rats. Hence, this present study was designed to evaluate the protective effect of the strong antioxidant, ... -
Determination of the relationship between rs4986790 and rs4986791 variants of TLR4 gene and lung cancer
Hülyam, Kurt; Özbayer, Cansu; Bayramoğlu, Ayşegül; Güneş, Hasan Veysi; Degirmenci, İrfan; Öner, Kevser Setenay; Metintaş, Muzaffer (Springer New York LLC, 2016)Chronic inflammation triggers DNA damage and oncogenic mutations and causes tumor formation and tumor progression. One of the important components of the inflammatory response is Toll-like receptor (TLR) family. The objective ... -
Effects of Interactions among Gene Polymorphisms of the Renin-Angiotensin-Aldosterone System on Hypertension in Turkish People from Southeast Anatolia
Arpacı, Abdullah; Küçük Urhan, Meral; Bayramoğlu, Ayşegül; Güler, Halil İbrahim; Ecevit, Hasret; Suner, Arif; Karakaş Çelik, Sevim (Univ Press, 2019)Introduction: Hypertension (HT) is characterized by high blood pressure. The reninangiotensin-aldosterone system (RAAS) plays a crucial role in blood pressure (BP) regulation by maintaining vascular tone and the water-sodium ... -
The effects of lycopene on hepatic ischemia/reperfusion injury in rats
Bayramoğlu, Gökhan; Bayramoğlu, Ayşegül; Altuner, Yılmaz; Uyanoğlu, Mustafa; Çolak, Suat (Springer, 2015)There is a very little information about the protective effect of lycopene (LYC) against hepatic ischemia-reperfusion injury. The present study was designed to examine the possible protective effect of the strong antioxidant ... -
Frequency of angiotensin II type 1 receptor gene polymorphism in Turkish acute stroke patients
Kurt, Hülyam; Bayramoğlu, Ayşegül; Güneş, Hasan Veysi; Özbabalık, Demet; Değirmenci, İrfan; Çolak, Ertuğrul; Coşan Turgut, Didem; Bayram, Banu; Dikmen, Miris (Wiley, 2013)This study was performed in acute stroke patients in the Turkish population to determine the frequency of the A1166C polymorphism in the AT1 gene and to examine the role of this polymorphism in acute stroke development. ... -
Gallic acid reduces experimental colitis in rats by downregulation of cathepsin and oxidative stress
Bayramoğlu, Gökhan; Şentürk, Hakan; Kanbak, Güngör; Canbek, Mediha; Bayramoğlu, Ayşegül; Dokumacıoğlu, Ali; Engür, Selin (Erciyes Univ Sch Medicine, 2020)Objective: Ulcerative colitis (UC) is an idiopathic inflammatory bowel disease (IBD) with common, repetitive inflammation of the colon and rectum, which is highly defined by loss of blood on colon mucosa, ulceration and ... -
Genetic variations of Renin-angiontensin and Fibrinolytic systems and susceptibility to coronary artery disease: a population genetics perspective
Bayramoğlu, Ayşegül; Bayramoğlu, Gökhan; Küçük Urhan, Meral; Güler, Halil İbrahim; Arpacı, Abdullah ([y.y.], 2020)BACKGROUND: Genetic predisposition is an important risk factor in coronary artery disease (CAD).This study was conducted to determine the polymorphism frequencies of the plasminogen activator inhibitor-1(PAI-1) gene 4G/5G, ... -
The hepatoprotective effects of Hypericum perforatum L. on hepatic ischemia/reperfusion injury in rats
Bayramoğlu, Gökhan; Bayramoğlu, Ayşegül; Engür, Selin; Şentürk, Hakan; Öztürk, Nilgün; Çolak, Suat (Springer, 2014)Little is known about the effective role of Hypericum perforatum on hepatic ischemia-reperfusion (I/R) injury in rats. Hence, albino rats were subjected to 45 min of hepatic ischemia followed by 60 min of reperfusion period. ... -
Investigation of relationship between IL-6 gene variants and hypertension in Turkish population
Karaman, Esin; Küçük, Meral Urhan; Bayramoğlu, Ayşegül; Göçmen, Semire Uzun; Ercan, Süleyman; Güler, Halil İbrahim; Küçükkaya, Yunus; Erden, Sema (Springer, 2015)Hypertension (HT) is a common and life threating health problem worldwide leading to stroke, heart attack and renal failure. It is characterized by elevated blood pressure forced heart load. Human interleukin-6 (IL-6) and ... -
Is there any genetic predisposition of MMP-9 gene C1562T and MTHFR gene C677T polymorphisms with essential hypertension?
Bayramoğlu, Ayşegül; Küçük, Meral Urhan; Güler, Halil İbrahim; Abacı, Okay; Küçükkaya, Yunus; Çolak, Ertuğrul (Springer, 2015)The current study was conducted to determine whether there is a relation between hypertension and two different polymorphisms, including C1562T of the Matrix metalloproteinase-9 (MMP-9) gene and C677T of the methylenetet ... -
Lycopene partially reverses symptoms of diabetes in rats with streptozotocin-induced diabetes
Bayramoğlu, Ayşegül; Bayramoğlu, Gökhan; Şentürk, Hakan (Mary Ann Liebert Inc., 2013)In the present study, we describe the effects of lycopene on the symptoms of streptozotocin (STZ)–induced diabetes in rats. Lycopene at the dose of 2.5 mg/kg body weight (bw) per day was orally administered to STZ-induced ... -
Plasminogen activator inhibitor-1 and susceptibility to lung cancer: a population genetics perspective
Bayramoğlu, Ayşegül; Güneş, Hasan Veysi; Metintaş, Muzaffer; Degirmenci, İrfan; Güler, Halil İbrahim; Üstüner, Cengiz; Musmul, Ahmet (Mary Ann Liebert Inc., 2014)Aim: The aim of this study was to investigate the polymorphism frequency of plasminogen activator inhibitor-1 (PAI-1) (rs1799889) 4G/5G in patients with lung cancer. Methods: In this study, 286 genomic DNAs (154 lung cancer ... -
Preventive role of gallic acid on hepatic ischemia and reperfusion injury in rats
Bayramoğlu, Gökhan; Kurt, Hülyam; Bayramoğlu, Ayşegül; Güneş, Hasan Veysi; Değirmenci, İrfan; Çolak, Suat (Springer, 2015)There is little information about the hepatoprotective effects of gallic acid against ischemia-reperfusion (I/R) damage. Animals were subjected to I/R. Gallic acid at doses of 50 and 100 mg/kg body weight (bw) were injected ... -
The role of NOD1/CARD4 and NOD2/CARD15 genetic variations in lung cancer risk
Özbayer, Cansu; Kurt, Hülyam; Bayramoğlu, Ayşegül; Güneş, Hasan Veysi; Metintaş, Muzaffer; Değirmenci, İrfan; Öner, Kevser Setenay (Springer Basel Ag, 2015)Background and aim NOD1/CARD4 and NOD2/CARD15 are members of the Nod-like receptor (NLR) family, and they contain a caspase recruitment domain (CARD). NLRs are located in the cytosol where they bind bacterial and viral ... -
The role of rs1799889 genetic variation in type 2 diabetes and diabetic nephropathy risk
Bayramoğlu, Ayşegül; Bayramoğlu, Gökhan; Güler, Halil İbrahim (Erciyes Univ Sch Medicine, 2020)AI-1 gene 4G/5G and to investigate the role of this polymorphism in T2 DM and DN development. Materials and Methods: The genomic DNA of the 261 individuals was included in this study. The polymerase chain reaction (PCR) ... -
Type 2 diabetes mellitus and diabetic nephropathy with angiotensin ii type 1 receptor gene variants: A case control study in a Turkish population
Bayramoğlu, Ayşegül; Bayramoğlu, Gökhan; Güler, Halil İbrahim; Hazar, Güleser (Kuwait Medical Association, 2020)Objective: This study was performed to determine the polymorphism frequencies of the Angiotensin II type 1 receptor (AT1) A1166C, and to examine the role of this polymorphism in type-2 diabetes (T2DM) and diabetic nephropathy ...