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dc.contributor.authorÇiçek, Ayşegül Çopur
dc.contributor.authorDüzgün, Azer Özad
dc.contributor.authorSaral, Ayşegül
dc.contributor.authorSandallı, Cemal
dc.date.accessioned2021-10-11T07:15:28Z
dc.date.available2021-10-11T07:15:28Z
dc.date.issued2014en_US
dc.identifier.citationÇiçek, A. C., Düzgün, A. O., Saral, A., & Sandallı, C. (2014). Determination of a novel integron‐located variant (bla OXA‐320) of Class D β‐lactamase in Proteus mirabilis. Journal of Basic Microbiology, 54(10), 1030-1035.en_US
dc.identifier.urihttps://hdl.handle.net/11494/3517
dc.descriptionThis work was partially supported by Recep Tayyip Erdogan University Research Fund Grants BAP-2009.102.03.2 and BAP-2011.102.03.3.en_US
dc.description.abstractProteus mirabilis (P. mirabilis) is one of Gram-negative pathogens encountered in clinical specimens. A clinical isolate (TRP41) of P. mirabilis was isolated from a Turkish patient in Turkey. The isolate was identified using the API 32GN system and 16S rRNA gene sequencing and it was found resistant to ampicillin/sulbactam, piperacillin, tetracycline, and trimethoprim/sulfamethoxazole. This isolate was harboring a Class 1 integron gene cassette and its DNA sequence analysis revealed a novel bla(OXA) variant exhibiting one amino acid substitution (Asn266Ile) from bla(OXA-1). This new variant of OXA was located on Class 1 integron together with aadA1 gene encoding aminoglycoside-modifying enzymes. According to sequence records, the new variant was named as bla(OXA-320). Cassette array and size of integron were found as bla(OXA-320)-aadA1 and 2086bp, respectively. The bla(OXA-320) gene is not transferable according to conjugation experiment. In this study, we report the first identification of bla(OXA-320)-aadA1 gene cassette, a novel variant of Class D -lactamase, in P. mirabilis from Turkey.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbla(OXA-320) geneen_US
dc.subjectClass D -lactamaseen_US
dc.subjectIntegronen_US
dc.subjectPen_US
dc.subjectmirabilisen_US
dc.titleDetermination of a novel integron-located variant (bla(OXA-320)) of Class D beta-lactamase in Proteus mirabilisen_US
dc.typearticleen_US
dc.relation.journalJournal of Basic Microbiologyen_US
dc.departmentAÇÜ, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümüen_US
dc.authorid0000-0002-7757-6812en_US
dc.identifier.volume54en_US
dc.identifier.issue10en_US
dc.identifier.startpage1030en_US
dc.identifier.endpage1035en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1002/jobm.201300264en_US
dc.contributor.institutionauthorSaral, Ayşegül


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