Yazar "Ayaz, Faik Ahmet" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • [ X ]
    Öğe
    Fatty acid composition of achenes of Cirsium taxa (Asteraceae, Carduoideae) from Turkey
    (Walter De Gruyter Gmbh, 2016) Özcan, Melahat; Ayaz, Faik Ahmet; Özoğul, Yeşim; Glew, Robert; Özoğul, Fatih
    The fatty acid compositions and total oil contents in achenes of 22 Cirsium taxa collected from different natural habitats in Turkey were investigated. The range of total fat in the taxa varied from 1.7% to 13.3%. The taxa contained palmitic (C16:0), stearic (C18:0), oleic (C18:1n-9), linoleic (C18:2n-6), and alpha-linolenic (C18:3n-3) acid. Polyunsaturated fatty acids had the highest level, ranging from 52.1% to 75.2% (C18:2n-6) and 0.5%-17.3% (C18: 3n-3). Total saturated (6.9%-17.4%), monounsaturated (11.7%-28.9%), and polyunsaturated (57.4%-79.9%) fatty acids varied substantially, whereas total unsaturated fatty acids ranged from 70.6% to 91.3%. Considerable variation was observed (P < 0.05) within each taxon for these fatty acids, especially alpha-linolenic acid (C18:3n-3). Fatty acid compositions of the 22 taxa were compared by cluster analysis (UPGMA) and principle component analysis (PCA) based on six major fatty acids. This is the first report on the lipid content and fatty acid composition of achenes of Cirsium taxa growing in different areas of Turkey. Fatty acid profiles, relative proportions and levels of fatty acids can be used as additional biochemical markers in the taxonomy of Cirsium.
  • Küçük Resim
    Öğe
    Fluoroquinolone-triazole hybrid molecules: A comparative analysis of conventional and green synthetic methods, and evaluation of their biological activities
    (John Wiley and Sons Inc, 2025) Ayvaz, Aslıhan; Demirbaş, Neslihan; Demirbaş, Ahmet; Ceylan, Şule; Çolak, Nesrin; Ayaz, Faik Ahmet; Kılıç, Ali Osman; Durukan, İnci; Kara, Yakup
    In this study, a series of 1,2,4-triazole derivatives was initially synthesized and subsequently incorporated into the fluoroquinolone scaffold via Mannich-type reactions. The reactions were conducted using conventional heating, ultrasound-assisted synthesis, and microwave irradiation techniques to determine the optimal reaction conditions. FTIR, NMR, and mass spectrometry analyses characterized the structures of the resulting compounds. Furthermore, the synthesized derivatives were assessed for their antimicrobial and antioxidant properties. Their inhibitory activities against key enzymes, urease, α-amylase, α-glucosidase, acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and tyrosinase, were also investigated, with several compounds exhibiting noteworthy bioactivity. Nearly all the synthesized hybrid compounds exhibited minimum inhibitory concentration (MIC) values comparable to standard antibacterial agents such as norfloxacin and ciprofloxacin. Except for 4-arylideneamino-1,2,4-triazole-3-one derivatives, all tested compounds demonstrated notable anti-urease activity. Furthermore, several newly synthesized molecules showed promising inhibitory effects against α-amylase and α-glucosidase enzymes.