Yazar "Keskin, Abdulkadir" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    Comparison of the impacts of medet omidi ne/Ke tamin e and medet omidi ne/Pr opofo l anesthesia and their reversal by atipamezole on echocardiographic values in dogs
    (İstanbul Üniversitesi Cerrahpaşa, 2022) Kibar, Murat; Keskin, Abdulkadir; Aytmirzakizi, Ayperi; Özturk, Zeynep
    The reaction of the cardiovascular system to anesthetics can be various and different, based on dosing, the experimental model, and agent sele-ction. A few studies have compared the effects of different anesthetic agents used for trans-thoracic echocardiography on cardiac functions in dogs; however, none of these studies examined the effects of different anesthetic regimes and their reversal by atipamezole echoc ardio graph icall y. The aim of this study was to investigate, visualize, and clarify in vivo both the short-term echocardiographic impacts of medet omidi ne-ke tamin e and medet omidi ne-pr opofo l anesthesia regimes and their reversal in dogs. Twenty sexually intact female dogs (weighing between 5.7 and 14.5 kg and 0.5-3 years of age) referred for ovariohysterectomy procedure from a local shelter at regular intervals over 3 months were included in the study. Echocardiographic measurements of the two-dimensional guided M-mode echocardiography were conducted with the dogs positioned in right lateral recumbence. Both groups showed declines in interventricu-lar septum percent, left ventricular diameter percent, and left ventricular ejection fraction after anesthesia induction (baseline vs. T1, all, p < .05); nevertheless, the reduction and starting pattern of interventricular septum percent, left ventricular diameter percent, and left ventricular ejection fra-ction presented important intergroup distinction. The echocardiographic values were affected significantly after anesthesia with medet omidine- ketamin e and medet omidi ne-pr opofo l; atipamezole can be useful for return to baseline values quickly and safely in dogs after abdominal sur-gery such as ovariohysterectomy.
  • Küçük Resim
    Öğe
    Effects of medetomidine/ketamine and xylazine/ketamine anesthesia and their reversal by atipamezole on ocular parameters and monitored anesthesia care in cats
    (Ankara Üniversitesi Veterinerlik Fakültesi, 2022) Kibar, Murat; Keskin, Abdulkadir; Aymirzakizi, Ayperi; Öztürk, Zeynep
    The aim of this study was to investigate the impact of the general anesthetic drug ketamine and premedication agents medetomidine and xylazine, and their reversal by atipamezole, on monitored anesthesia care values and ocular parameters such as intraocular pressure, horizontal pupillar diameter, and Schirmer tear test in cats. A randomized, single-blinded study was conducted. Twenty intact female cats (weiging between 2.2 and 3.6 kg, and 0.5 to 5.5 years of age) referred for ovariohysterectomy (OHE) procedure by the owners at regular intervals over 4 months were included in the study. The cats were randomly divided into two groups containing 10 animals in each group. The cats were premedicated with medetomidine 80 µg/kg intramuscular in group 1 while the cats in the 2nd group were premedicated with xylazine hydrochloride 2 mg/kg intramuscular. After the OHE procedure was ended, anesthesia regimes were reversed by using atipamezole 200 µg/kg intramuscularly. Monitoring of respiration rate, heart rate, mean arterial pressure, peripheral arterial oxygen saturation, and body temperature were conducted using a patient monitor at T0, T1, T2, T3, and T4 time points. Both groups showed declines in intraocular pressure and increases in horizontal pupil diameter after anesthesia induction (T0 vs. T1, all, P<0.05); however, the chancing and recovery pattern of intraocular pressure and horizontal pupil diameter showed intergroup difference. In conclusion, xylazine/ketamine is more effective than medetomidine/ketamine in attenuating the intraocular pressure, increasing the horizontal pupil diameter, and alteration the monitored anesthesia care response in the general anesthesia.