Artvin MYO Koleksiyonu Yayın Koleksiyonu

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https://hdl.handle.net/11494/1067

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Ticari sumak meyveleri ile Artvinde yayılış gösteren doğal sumak (Rhus Coriaria L.) meyvelerinin fizikokimyasal analizlerinin karşılaştırılması
(Turkish Science and Technology Publishing (TURSTEP), 2025) Konanç, Mustafa Umut
This study aimed to compare the physicochemical and bioactive properties of natural sumac (Rhus coriaria L.) fruits from the Artvin region with those of commercially available sumac. Both sample types were analyzed for moisture, fat, protein, carbohydrate content, pH, titratable acidity, total phenolic and flavonoid contents, and trace element concentrations. The findings revealed that natural sumac had a higher fat content (28%) and a lower pH (2.92) than commercial samples. Moreover, it exhibited significantly higher total phenolic (47.95 mg GAE/g) and tannin (23.46 mg catechin/g) contents, while flavonoid levels showed no significant difference. Trace element analysis indicated that commercial sumac had higher concentrations of zinc (10.87 mg/kg) and copper (1.78 mg/kg), whereas natural sumac was richer in iron (255.65 mg/kg), magnesium (788.4 mg/kg), and manganese (17.41 mg/kg). These results underscore the superior nutritional and antioxidant potential of natural sumac, highlighting its possible applications in the food, pharmaceutical, and cosmetic industries.
Endüstriyel bazı levhaların CNC makinası ile farklı kesme derinliklerine göre frezelenmesi işleminin ahşap toz emisyonununa etkisil
(BÜLENT VEREP, 2025) Çakıroğlu, Evren Osman
Günümüzde kullanımı sürekli artan endüstriyel levhalar mobilya ve iç mekan donatılarında önemli bir yer edinmiştir. Bu çalışmada orta yoğunlukta lif levha (MDF), yönlendirilmiş yonga levha (OSB) ve yongalevha (PB) endüstriyel levhaların CNC makinası ile farklı kesme derinliklerine göre frezelenmesinde ahşap toz emisyonuna etkisinin belirlenmesi amaçlanmıştır. CNC makinasının farklı kesme derinliklerine göre (2-3-4 mm) oluşturduğu ahşap toz miktarları incelenmiştir. Ahşap tozu emisyonlarının PM2.5, PM10 belirlenerek analizleri yapılmıştır. Bu çalışma, kesme derinliğinin PM üzerinde önemli bir etkiye sahip olduğunu göstermektedir. PM2.5 ve PM10 ortalama değerlerine göre en yüksek ahşap toz emisyonu OSB’de 2 mm kesme derinliğinde sırasıyla 68.90 µg/m³ ve 92.83 µg/m³ olarak ölçülmüştür. En düşük ahşap toz emisyonu ise yongalevhada 3 mm kesme derinliğinde sırasıyla PM2.5 ve PM10 ortalama değerlerine göre 40.43 µg/m³ ve 60.48 µg/m³ değerlerinde ölçülmüştür. Bu çalışmayla birlikte insan sağlığı açısından zararlı olan ahşap tozlarına maruz kalma durumlarını azaltılarak MDF, OSB ve yongalevha için diğer kesme parametreleri de düşünülerek en uygun kesme derinlikleri önerilebilecektir.
Geleneksel ahşap Şavşat evinin sürdürülebilirliği: Artvin Çoruh Üniversitesi örneği
(Artvin Çoruh Üniversitesi, 2025) Çakıroğlu, Evren Osman; Taşdemir, Taner; Çakıroğlu, Birgül
Kırsal mimari ve ahşap yapıları bünye-sinde barındıran Doğu Karadeniz Bölgesi’nin özgün öğelerinden biri olan “Şavşat Evleri” mimarisi ve ahşap kullanımı ile önem arz etmektedir. Çalışmanın amacı; bu ahşap yapıların kırsal mimaride korunması konusuyla birlikte kent mekânlarında da sürdürülebilirliğini sağlayarak farkındalık oluşturmaktır. Bu bağlamda Artvin-Şavşat yöre mimarisinde geleneksel yerleşim, plan, ahşap mimari oluşumuna sahip olan Şavşat Evleri ve geleneksel yapım teknikleri araştırılıp incelenmiştir. Bu inceleme sonucunda Artvin Çoruh Üniversitesi bünyesindeki bir mekâna Şavşat Evi mimarisi ve ahşap uygulama teknikleriyle özgün, kullanım yeri ve amacı farklı olan bir ahşap yapı inşa edilmiştir. Bu ahşap yapının inşasında yöre de bulunan Sarıçam (Pinus sylvestris L.) ağaç türünden faydalanılmıştır. Ahşap parçaların birleştirilmesinde geçme tekniği kullanılmıştır. Ahşap kapıların tasarımında yöresel motiflerden yararlanılmış, köşk ve balkon bölümünde ise Şavşat evine özgü motifler araştırılarak uygulanmıştır. Mevcut araştırmada sarıçam ağaç malzemesinin geçme birleştirmelerinde, koruyucu boya tutmada ve bazı süsleme işlemlerinde iyi sonuçlar verdiği görülmüştür.
Kızıl Geyik (Cervus elaphus) Aktivite Desenlerinin Belirlenmesi: Samsun-Vezirköprü Yöresi Örneği
(Bartın Üniversitesi Orman Fakültesi, 2025) Uçarlı, Yasin
Yaban hayvanlarının aktivite desenlerinin belirlenmesi özellikle etkin bir yaban hayatı planlaması için önemlidir. Bu çalışmada Samsun-Vezirköprü yöresinde kızıl geyik (Cervus elaphus) popülasyonlarının günlük aktivite desenleri ile ekolojik etkileşim içerisinde oldukları türlerin belirlenmesi amaçlanmıştır. Araştırma alanında yaklaşık 250 gün süren fotokapan ile izleme çalışması yapılmıştır. Çalışmada kızıl geyik, karaca (Capreolus capreolus), yaban domuzu (Sus scrofa), kurt (Canis lupus) ve vaşak (Lynx lynx) gibi önemli memeli türler tespit edilmiştir. Kızıl geyiklerin sabah alacakaranlık vakitlerinde %39 oranı ile daha fazla aktif olduğu tespit edilmiştir. Kurtların akşam alacakaranlık vakitlerinde %33 oranında, yaban domuzunun ise gece vakitlerinde %46 oranı ile daha fazla aktif oldukları belirlenmiştir. Yapılan istatistiksel analizlerde yaban hayvanlarının aktivite desenleri bakımından türler arasında anlamlı farklılıklar tespit edilmiştir. Bu çalışma yaban hayvanlarının aktivite desenlerinde tür, mevsim ve günün saati gibi değişkenlerin rol oynadığını göstermiştir. Özellikle yoğun ormancılık uygulamalarının yapıldığı bölgelerdeki planlamalarda yaban hayvanlarının aktivite desenlerinin dikkate alınması orman ekosistemlerinin bir bütün olarak daha etkin korunmasına katkı sağlayacaktır.
1960’dan sonra sanatta metaforik anlatıma zemin hazırlayan tarihsel süreç
(ANKARA HACI BAYRAM VELİ ÜNİVERSİTESİ, 2025) Coşkun, Meral; Alper Akçay, Ayça
19. yüzyılın ikinci yarısından itibaren büyük savaşlar ve toplumsal değişimler, sanatın içeriğini ve işlevini derinden etkilemiştir. Endüstri Devrimiyle birlikte sanatçılar yeni malzemeler ve teknikler deneyerek geleneksel sanat anlayışından uzaklaşmaya başlamışlardır. Bu büyük değişim sanatın içeriğini ve işlevini değiştirirdi. Sanatçılar endüstriyel çağın getirdiği yeni malzemeleri kullanarak yeni teknikler denedikleri deneysel bir döneme girdiler. Bu süreçte cinsiyet rolleri, tüketim kültürü ve sınıf farkları gibi konular üzerine yoğunlaşan sanatçılar, farklı ifade biçimleri geliştirmişlerdir. 1960 sonrası dönemde sanat, estetik boyuttan kavramsal boyuta geçerek metaforik anlatım biçimlerinin öne çıktığı yeni bir döneme girmiştir. Bu çalışma, 19. yüzyılın ikinci yarısından itibaren modern sanat akımlarında sanatçıların kullandığı hazır nesneler ve metaforik anlatım biçimlerini, sanatçılar ve eserler üzerinden literatür taraması ile incelemeyi amaçlamaktadır.
Analysis of companies’ intellectual capital performance using the MEREC-based MARCOS method: The case of the BIST forest, paper and printing index
(Düzce Üniversitesi, 2025) Ersen, Nadir; Akyüz, İlker; Akyüz, Kadri Cemil
This study aims to measure and comparatively rank the intellectual capital performance of companies in the BIST Forest, Paper, and Printing Index by developing the MEREC–MARCOS integrated method, which will contribute to the literature in the field of multi-criteria decision making (MCDM).The study used decision matrices generated from financial data for the years 2020–2024. Criteria weights were determined using the MEREC method, and company performance rankings were performed using the MARCOS method. The reliability of the method was tested using comparative analysis using WASPAS, COPRAS, SAW, and MOOSRA methods, and the Spearman rank correlation coefficient. The analyses revealed that the criteria weights change periodically. While the Intangible Assets (K8) criterion was of the highest importance in 2020–2021, the Market Value–Book Value (K5) criterion gained prominence in subsequent years. In the company rankings, ALKA achieved the highest performance between 2022 and 2024, while DGNMO and MNDTR experienced a decline in performance. The Spearman correlation coefficient averaged 0.95, demonstrating high agreement between the methods. The MEREC–MARCOS method is an effective tool for objective, reliable, and comparative assessment of intellectual capital performance. The method can be adapted to different sectors and decision-making problems, and more flexible decision support systems can be developed by integrating it with fuzzy logic or artificial intelligence-based approaches.
Metanol–su karışımlarının elektrosprey soğutma ile optimum çalışma koşullarının Taguchi Metoduyla belirlenmesi
(Recep Tayyip Erdoğan Üniversitesi, 2025) Sönmez, Fatin; Öztürk, Ahmet
Bu çalışmada, düz plaka bir ısı alıcı üzerinde elektrosprey soğutma sisteminin ısıl performansı, Taguchi deney tasarımı kullanılarak optimize edilmiştir. Deneyler, 4 kW/m² sabit ısı akısı altında, 50×50×4 mm boyutlarında alüminyum ısı alıcı, 25G paslanmaz çelik nozul ve 30 mm sabit nozul–ısı alıcı mesafesi ile gerçekleştirilmiştir. Çalışmada soğutucu akışkan olarak %100 metanol, %90 metanol–%10 su ve %80 metanol–%20 su karışımları; debi olarak 20, 30 ve 40 ml/h; gerilim olarak ise 7, 10 ve 13 kV seviyeleri kullanılmıştır. L9(3^3) ortogonal dizisine göre oluşturulan Taguchi planı kapsamında elde edilen ΔT değerleri üzerinden regresyon ve varyans analizleri yapılmıştır. Sonuçlar, toplam varyansın %95,03’ünün model tarafından açıklandığını ve en etkili parametrelerin sırasıyla debi (%53,45 katkı) ve akışkan türü (%33,21 katkı) olduğunu göstermiştir; gerilimin katkısı ise %8,38 ile daha sınırlı kalmıştır. Sinyal/gürültü oranı analizine göre optimum çalışma koşulları %80 metanol–%20 su karışımı, 40 ml/h debi ve 13 kV gerilim olarak belirlenmiştir. Bu koşullarda elde edilen ΔT=12,54 °C ve h=318,98 W/m²K değerleri, elektrosprey soğutmanın yüksek ısıl performans sağladığını ortaya koymaktadır. Bulgular, debi ve akışkan bileşiminin elektrosprey soğutma tasarımında kritik rol oynadığını, gerilimin ise bu parametrelerle etkileşimli ikincil bir etkiye sahip olduğunu göstermektedir.
Antioxidant properties of propolis: The systematic and bibliometric analyses of research trends in the last decade (2015-2024)
(SPRINGER, 2025) Bozkuş, Tuğba Nigar
Propolis, a resinous substance produced by bees, has garnered significant scientific interest due to its diverse biological activities, particularly its antioxidant properties. This research addresses a notable gap in the literature by providing a comprehensive overview of research trends related to the antioxidant activity of propolis, analyzing 321 articles published in 142 journals between 2015 and 2024. The study reveals a substantial and growing body of research in this area, with a notable increase in publications over the past decade. While Apis mellifera propolis remains the most frequently studied type, there is a growing interest in propolis from stingless bees. The analysis highlights the predominance of studies focusing on Brazilian, Chinese, and Turkish propolis, reflecting regional research interests and propolis availability. A wide range of methodologies are employed, with spectroscopy, chromatography, and in vitro antioxidant assays being the most prevalent. Ethanol is the most used extraction solvent, although alternative methods are being explored. Keyword analysis and thematic mapping reveal a strong emphasis on chemical characterization, particularly the identification and quantification of phenolic compounds, and their relationship to antioxidant capacity. Research priorities have clearly evolved over the past decade. Studies are now moving beyond basic characterization to focus on optimizing extraction methods and exploring novel applications. The study identifies key research gaps, including the necessity of harmonization of methodologies, more comprehensive investigations of stingless bee propolis, and increased focus on in vivo and clinical studies to translate in vitro findings into practical applications. This analysis provides valuable data for researchers, highlighting key areas for future investigation and promoting a more focused and impactful approach to propolis research.
Comparative mitogenome sequences and phylogenetic relationships of two mongooses (Herpestes ichneumon and Urva auropunctata) from Turkiye and Iraq
(SPRINGER HEIDELBERG, 2025) Yıldız, Barış; Selçuk, Ahmet Yesari; Naji, Ahmed Qasim; Şeker, Perinçek Seçkinozan; Baran, Mehmet; Teber, Saffet; Al-Abbasi, Husham Abdulrahman Mahdi; Tez, Coskun; İbiş, Osman
Mongoose species (Herpestidae) exhibit a wide geographic distribution across Africa, Asia, and several island regions, yet mitogenomic data remain scarce for many taxa and regions. In this study, the complete mitochondrial genomes of the Egyptian mongoose (Herpestes ichneumon) from Turkiye and the small Indian mongoose (Urva auropunctata) from Iraq are analyzed for the first time to explore their genetic structure and phylogenetic relationships within the Herpestidae. The mitogenomes are similar in overall organization and size (16,660 bp in H. ichneumon and 16,761 bp in U. auropunctata), with variations primarily found in the D-loop (control region), which influences genome length through repeated motifs. The Maximum Likelihood (ML) and Bayesian Inference (BI) phylogenetic analyses using complete mitochondrial genome and cytochrome b (CYTB) sequences reinforce the previous findings on Herpestidae phylogeny. Results support the division of Herpestidae into two subfamilies (Herpestinae and Mungotinae), confirm the monophyly of Urva, and highlight the paraphyly of Herpestes. Based on the complete mitogenome sequences, the Iraqi U. auropunctata specimens are clustered with Japanese and Fijian specimens, indicating low level of intraspecific variation. Herpestes ichneumon is clustered with the Galerella sanguine based on the mitogenome sequences. Additionally, H. ichneumon haplotypes are grouped into three haplogroups (Iberian, Levantine, and South African) based on the CYTB sequences, reflecting regional genetic differentiation. Molecular dating estimated Herpestidae diverges from Eupleridae similar to 30.76 million years ago (Mya), with subfamily divergence occurring in the Early Miocene (similar to 19.87 Mya). Within Urva, species begin diverging around 12.5 Mya, with U. javanica and U. auropunctata separating similar to 4.67 Mya. Recent divergence is also noted between H. ichneumon specimens from Turkiye and Lebanon (similar to 150 Kya) and among U. auropunctata populations from Iraq, Japan, and Fiji (similar to 600 Kya), supporting ongoing intraspecific diversification within both species. This study provides valuable insights into the phylogeny and evolutionary history of two mongoose species by comparing the structural and organizational features of their mitogenomes from biogeographically related regions, along with phylogenetic and evolutionary dating analyses based on complete mitogenome and CYTB sequences.
Effects of fat ratio and cooking method on the formation of polycyclic aromatic hydrocarbons in a semi-dry fermented sausage
(TAYLOR & FRANCIS LTD, 2025) Kırkyol, Mine; Akköse, Ahmet; Kaban, Güzin; Kaya, Mükerrem
The study examined the effects of fat ratios (10, 20, and 30%), cooking methods (hot plate and barbecue), and cooking degree (raw, rare, medium, or well) on the levels of polycyclic aromatic hydrocarbons (PAHs) and some physicochemical properties in a semi-dry fermented sausage, heat-treated sucuk (HTS). While the pH value increased depending on the cooking degree, moisture and fat contents decreased as the cooking degree increased. Fat ratio, cooking method, and cooking degree significantly affected the moisture retention, fat retention, and cooking yield of the samples (p < 0.01). The levels of benzo[a]pyrene (BaP) and total PAH4 (benzo[a]pyrene + benzo[a]anthracene + benzo[b]fluoranthene + chrysene) increased depending on the fat ratio and cooking degree. Moreover, barbecuing caused higher BaP and PAH4 formation. Similar results were also obtained for total PAH8 and PAH16 contents.
Physicochemical characterization and bioactive profile of wild Demir Apple (Malus sylvestris) from the Eastern Black Sea Region
(WILEY-V C H VERLAG GMBH, 2025) Çelebi, Zeynep Berin; Tunca, Erol; Kesemen, Ali Murat; Kolaylı, Sevgi
This study characterized the physicochemical properties, bioactive composition, and antioxidant capacity of the wild Demir apple (Malus sylvestris), an endemic genotype from the Eastern Black Sea region. Samples collected from Artvin were analyzed for physical and chemical attributes, including total soluble solids (13.87%), titratable acidity (0.43% malic acid), ascorbic acid (5.93 mg/100 g FW), and total sugars (11.94%). High-performance liquid chromatography (HPLC-PDA) revealed chlorogenic acid, epicatechin, and catechin as the predominant phenolic compounds. The total phenolic and flavonoid contents were 103.98 mg GAE/100 g FW and 2.09 mg QUE/100 g FW, respectively, while antioxidant capacity, assessed via FRAP and DPPH assays, was 2635.91 mu mol FeSO4/g and 7.75 mg/mL. These findings highlight the wild Demir apple as a rich source of bioactive compounds with strong antioxidant potential, supporting its value for nutritional and functional food applications.
Global research trends in wood pellets, a renewable energy source: A bibliometric analysis
(Lukasiewicz Research Network, 2025) Akyüz, İlker; Ersen, Nadir; Bardak, Selahattin; Polat, Kinyas; Acar, Mustafa
Due to global warming and climate change, more importance has started to be attached to renewable energy sources as alternatives to fossil fuels. Wood pellets are among the renewable energy sources, and have been the subject of a growing number of studies. Therefore, developments and trends in research on wood pellets can be determined through bibliometric analysis of publications. This study explores the current status and "hot topics" of research on wood pellets using performance analysis and scientific mapping based on publications from 1980-2023. For this purpose, we carried out a bibliometric analysis of 758 publications in the Web of Science database scanned with the keywords "wood" and "pellets". The numbers of publications and citations on wood pellets have grown steadily over the years, with 67% of publications and 89% of citations coming in the last decade. A total of 2,294 authors from 884 organizations and six continents have contributed publications in the field of wood pellets. The University of British Columbia (Canada) and the United States Department of Energy (USA) were the institutions with the most numerous and the most cited publications. Sokhansanj Shahab from the University of British Columbia was the most active and most cited author. The published literature has focused on three topics: biomass, bioenergy, and combustion. As a result, this study will provide a general perspective for future research relating to wood pellets.
Determining optimal road widths in zoning plans using the LSM: Evidence from Elazığ, Türkiye
(NATL INST SCIENCE COMMUNICATION-NISCAIR, 2025) Taşkaya, Selim; Xu, Jiajun
Zoning plans encompass areas where people reside and fulfill their essential functions. The formulation of these plans is governed by various criteria, encompassing population, topography, land slope, aspect, climatic conditions, transportation, and opportunities for health and education. In T & uuml;rkiye, the zoning plan governed by Law No. 3194 is developed around zoning islands, incorporating various criteria during its formulation. Within such plans, transportation networks are established through primary and intermediate roads, which are designed not according to private property boundaries but in response to the configuration of zoning islands and site-specific land conditions. Consequently, this study investigates the necessity of determining road widths with varying characteristics-such as population, precedent, height, and construction coefficient-to optimize both traffic flow and pedestrian safety. By utilizing the Least Squares Method (LSM), main road widths are treated as correction coefficients; the constant width lengths, length coefficients, and all relevant criteria of zoning blocks are expressed separately as constants and unknowns, with their relations examined. The results provide an evaluation of road network design, emphasizing that the determination of ideal road width is a critical factor in enhancing the performance of zoning plans, offering place- and evidence-based guidance to strengthen long-term functional efficacy and urban resilience.
From home to health: The effectiveness of otago exercise program via telerehabilitation on fall-related outcomes in older adults
(ROMANIAN ASSOC BALNEOLOGY, 2025) Şimşek, Kubilay; Alptekin, Hasan Kerem; Hatık, Sefa Haktan; Pehlivanoğlu, Berkay Eren
This study aimed to investigate the effects of the Otago Exercise Program (OEP), delivered via telerehabilitation, on pain, walking speed, lower extremity muscle strength, fear of falling, anxiety, quality of life, and balance in older adults with a history of falls. A total of 45 participants aged 65-78 were randomized into three groups: Face-to-Face Otago Exercise Group (FFOEG, n=15), Telerehabilitation-Based Otago Exercise Group (TBOEG, n=15), and Control Group (CG, n=15). The intervention consisted of 45-minute sessions, three times per week, for eight weeks. Evaluations were performed at baseline, 4th week, 8th week, and 4 weeks post-intervention using the Numeric Pain Scale, Timed Up and Go Test, 30-Second Sit- to-Stand Test, Falls Efficacy Scale, Beck Anxiety Inventory, WHOQOL-OLD, and Tinetti Balance and Gait Test. No significant difference was found in demographic variables between the groups (p>0.05). Intra-group analyses showed significant improvements in both intervention groups in most outcomes (p<0.05). Between-group comparisons revealed significant differences in favor of TOEG for fear of falling and balance (p<0.05). These findings support the effectiveness of OEP and suggest that telerehabilitation may be a viable alternative for delivering fall-prevention exercises to older adults in hard-to-reach areas.
Molecular phylogeny of medicinal-aromatic plant Osmanthus decorus from Artvin, Türkiye
(KASTAMONU UNIVERSITY, 2025) Akyıldırım Beğen, Hayal; Eminağaoğlu, Özgür; Şeker, Perinçek Seçkinozan; Selçuk, Ahmet Yesari; Yakın, Batuhan Yaman; Tekiner Aydın, Nasibe; Saral Sarıyer, Ayşegül; Sarıyer, Emrah
Aim of study: The white flowers of Osmanthus species have been valued for centuries in medicinal and aromatic applications due to their distinct fragrance and chemical composition. Among the 27 species distributed globally, Osmanthus decorus is the only species endemic to the Caucasus region, found in Russia, Georgia, and Türkiye. O. decorus has a distinct distribution area around Artvin but has not been sufficiently studied at the molecular level regarding its differentiation from other species. Material and method: This study focuses on identifying the molecular differences between Turkish O. decorus samples and other species while constructing their phylogenies. Phylogenetic relationships were analyzed using Bayesian inference with universal DNA barcode markers (nrDNA ITS and cpDNA matK). Main results: The nuclear and chloroplast data were consistent, and all Caucasian Osmanthus specimens clustered into a strongly supported monophyletic group. As a result of the Bayesian analysis, it was determined that O. decorus does not clearly separate from other species within the genus. Research highlights: According to the results of BLAST analysis, it was determined that the samples from Russia and Georgia, which are geographically close to the samples from Türkiye, were 100% matched.
Assessing effects of forest fires on plant nutrients and biomass in northeastern Türkiye
(Taylor and Francis Ltd., 2025) Sağlam, Bülent; Uçarlı, Yasin; Aybar, Mustafa; Yılmaz, Fatma Nur
Forest fires have the potential to greatly impact both flora and fauna and are therefore one of the key regulators of ecosystem sustainability. The primary aim of this research was to assess the impact of forest fires on plant nutrients and weight in Scots pine (Pinus sylvestris) forests in the Northeastern Türkiye. Plant samples were collected from designated burned and control plots in the research region in May and August season. The weight of the plants was measured both after drying in an oven and after air-drying. Subsequently, the plant samples were analyzed to determine the levels of Ca, Fe, Mg, Na, K, C, H, N, and S nutrients. The results revealed that the levels of all nutrients were greater in the burned area compared to the control plots. Furthermore, Ca, Fe, Mg, H, and N content exhibited statistically significant disparities when compared to the control plots. The N% content in the burned area during the month of May was 5.57, while in the control plot it was 4.97. This study also demonstrated that prescribed fire may effectively enhance plant nutrients contents and a tool for sustainable use of forest resources.
Methylpiperazine-based 1,2,4-triazole derivatives as potent DNA gyrase b inhibitors with promising broad-spectrum antimicrobial activity
(Pleiades Publishing, 2025) Uygun Cebeci, Yıldız; Keşkek Karabulut, Yasemin; Ceylan, Şule
Abstract: The emergence of antimicrobial resistance (AMR) poses a critical threat to global health, underscoring the need for new antimicrobial agents. In this study, a novel series of 1,2,4-triazole derivatives was synthesized from methylpiperazine intermediates via esterification, hydrazide formation, thiourea condensation, and Mannich-type reactions. Structural characterization was performed using FT-IR, 1H, 13C NMR, and EI-MS techniques. Antimicrobial activities of the synthesized compounds were evaluated via broth microdilution. One derivative displayed remarkable broad-spectrum activity with MIC values <0.24 µg/mL against E. coli, S. aureus, M. smegmatis, and C. albicans. Molecular docking against E. coli DNA gyrase B (PDB: 4PRV) revealed strong binding affinities for two derivatives (–9.9 and –9.8 kcal/mol), correlating well with in vitro results. Key interactions included hydrogen bonding, π–π stacking, and halogen bonding. SAR analysis emphasized the role of electron-withdrawing and hydrophobic groups in enhancing activity. These triazole derivatives show promise as potent antimicrobial candidates targeting DNA gyrase B.
Molecular diversity of lupane hybrids in drug design and materials science
(Multidisciplinary Digital Publishing Institute (MDPI), 2025) Lipson, Victoria V.; Shirobokova, Maria G.; Gümüş, Mustafa Kemal; Öztürkcan, Arda; Chebanov, Valentyn A.
The need for new, more effective drugs to treat cancer, infectious diseases, various parasitic infestations, and metabolic disorders requires innovative approaches to the design of promising molecules. One of these areas is the creation of hybrid structures. Lupane triterpenoids are of significant interest for such research due to their high abundance in natural sources and their renewable nature, their molecular architecture, presence of several easily modifiable functional groups, enantiomeric purity, broad spectrum of biological activity, and low toxicity. Active research into the biological properties of new pentacyclic triterpenoid derivatives, not only of the lupane series but also of the oleonane and ursane series, is evidenced by the large number of reviews and experimental studies devoted to this topic. Our interest in the modification of lupanoids stems not only from the search for biologically active compounds but also from the development of functional materials. However, the materials science aspects of lupanoid applications are virtually unknown in literature. We have tried to fill this gap and examined the possibility of using betulin derivatives to create advanced materials. The high lipophilicity and nanoscale molecular structure of these compounds make them highly promising as chiral dopants in liquid crystal compositions and organogel components.
Taguchi based parameters optimization in electrospray cooling with mixed working fluids
(Pushpa Publishing House, 2025) Kabakuş, Abdüssamed
The rapid increase in power density of modern electronic devices has made compact and effective cooling strategies indispensable. In this work, the Taguchi experimental design method was employed to optimize electrospray cooling performance. Experiments were conducted with a constant nozzle diameter and a fixed nozzle-to-heat sink distance, using three different working fluids (100% ethanol, 90% ethanol-10% water, and 80% ethanol-20% water), flow rates between 0.3-0.5 ml/min, and applied voltages ranging from 6-10 V. The temperature difference (ΔT) was used as the primary evaluation parameter. Analysis of variance indicated that fluid composition and flow rate significantly influence cooling efficiency, whereas voltage plays a relatively minor role. The most favorable operating condition was identified as 80% ethanol-20% water at 0.5 ml/min and 6 V.
Morphological, linear and geometric morphometric differences of Anatolian Sorex (Mammalia: Soricidae) species
(Elsevier GmbH, 2025) Selçuk, Ahmet Yesari; Kaya, Alaettin; İbiş, Osman; Tez, Coşkun; Kefelioğlu, Haluk
The taxonomic complexity of Sorex species is largely due to their morphological similarity. The different approaches used in taxonomic studies have both advantages and disadvantages. In this study, Sorex volnuchini, Sorex raddei and Sorex satunini specimens were compared using morphological features (molar teeth), mechanical potential (bite force), linear morphometric and geometric morphometric analysis. No pigmentation was detected in the hypoconic region of the first upper molar in the samples of S. volnuchini. In contrast, the pigmentation in the hypoconic region showed variability in the samples of S. raddei and S. satunini. In linear morphometric analyses, the linear measurement results of craniodental and mandibular characters for S. raddei and S. satunini overlapped many characters. However, regarding linear measurements, S. volnuchini was separated from these species (p < 0.01). Based on both linear morphometrics and centroid size (geometric morphometrics), it was determined that S. volnuchini was smaller than other the Sorex species, and similarly, it was also determined that S. volnuchini had a lower bite force (mechanical potential) than other Sorex species. There was no correlation between bite force and centroid size (CS) within the species. However, pairwise comparisons determined a statistically significant difference among the species. The Jackknifed classification rate was over 92 % in linear morphometric analysis. As a result of geometric morphometric analysis, the order of the centroid size for the skull (ventral and dorsal) and the mandible was Neomys milleri > S. raddei > S. satunini > Sorex volncuhini. No significant difference was found between S. raddei and S. satunini in centroid size for only dorsal skull. Allometric growth, which varies in shape with size, was not observed in the skull (ventral and dorsal) and mandible. N. milleri, S. raddei, S. satunini and S. volnuchini differed according to the Procrustes and Mahalanobis distance (p < 0.05). Three dendrograms of morphological (ventral and dorsal skull, mandible) proximity showed a similar topology.

Güncel Gönderiler