Microwave-assisted synthesis of some hybrid molecules derived from morpholine and investigation of their antimicrobial activities
Yükleniyor...
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-VCH Verlag GmbH
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
2H-1,2,4-triazol-3(4H)-one compound was obtained starting from 4-(2-fluoro-4-nitrophenyl)morpholine via several steps. Then, these compounds were converted to the corresponding fluoroquinolone hybrids via one pot three component Mannich reaction. Moreover, the synthesis of eleven compounds, which can be considered as conazole analogues, was performed starting from 1,2,4-triazole-3-one compounds via three steps by either conventional or microwave mediated conditions. The effect of different solvents and microwave power on microwave prompted reactions was examined as well.
Açıklama
Anahtar Kelimeler
Antimicrobial activity, Conazole, Fluoroquinolone, Microwave, Morpholine, 1,2,4-triazole
Kaynak
ChemistrySelect
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
2
Sayı
35
Künye
Cebeci, Y. U., Ozdemir, S. B., Demirbas, A., Demirbas, N., Ceylan, S., Bayrak, H., & Alpay-Karaoglu, S.. (2017). Microwave-Assisted Synthesis of Some Hybrid Molecules Derived from Morpholine and Investigation of Their Antimicrobial Activities. ChemistrySelect, 2(35), 11402–11407. https://doi.org/10.1002/slct.201702097
