The role of rs1799889 genetic variation in type 2 diabetes and diabetic nephropathy risk

Basit Öğe Kaydı
dc.authorid0000-0001-8567-807Xen_US
dc.authorid0000-0003-2779-6478en_US
dc.authorid0000-0002-7261-6790en_US
dc.contributor.authorBayramoğlu, Ayşegül
dc.contributor.authorBayramoğlu, Gökhan
dc.contributor.authorGüler, Halil İbrahim
dc.date.accessioned2021-01-21T09:32:53Z
dc.date.available2021-01-21T09:32:53Z
dc.date.issued2020
dc.departmentAÇÜ, Sağlık Bilimleri Fakültesien_US
dc.descriptionArtvin Coruh University M80.02.01en_US
dc.description.abstractAI-1 gene 4G/5G and to investigate the role of this polymorphism in T2 DM and DN development. Materials and Methods: The genomic DNA of the 261 individuals was included in this study. The polymerase chain reaction (PCR) method with 4G and 5G allele-particular primers was used to identify the polymorphism of PAI-1 4G/5G. The PCR products were evaluated using a CCD camera after 2% agarose gel electrophoresis. Results: Although the frequencies of the gene genotypes differed statistically significant between 80 patients and 51 patients with and without DN, respectively, and the control group, no statistically significant difference was detected between those with and without DN. The 5G/5G genotype was found to be significantly higher in the patient group. Conclusion: The findings suggest that there is a significant correlation between variants of the PAI-1 gene and the risk for T2 DM formation.
dc.identifier.citationBayramoğlu, A., Bayramoğlu, G., & Güler, H. İ. (2020). The Role of rs1799889 Genetic Variation in Type 2 Diabetes and Diabetic Nephropathy Risk. Erciyes Medical Journal/Erciyes Tip Dergisi, 42(4), 441-446.en_US
dc.identifier.doi10.14744/etd.2020.04378
dc.identifier.endpage446en_US
dc.identifier.issue4en_US
dc.identifier.startpage441en_US
dc.identifier.urihttps://hdl.handle.net/11494/2562
dc.identifier.volume42en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorBayramoğlu, Gökhan
dc.institutionauthorBayramoğlu, Ayşegül
dc.language.isoenen_US
dc.publisherErciyes Univ Sch Medicineen_US
dc.relation.ispartofErciyes Medical Journal/ Erciyes Tip Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/us/*
dc.subjectType-2 diabetesen_US
dc.subjectDiabetic nephropathyen_US
dc.subjectPAI geneen_US
dc.subjectrs1799889en_US
dc.titleThe role of rs1799889 genetic variation in type 2 diabetes and diabetic nephropathy risken_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
aysegül_bayramoglu_2020.pdf
Boyut:
200.67 KB
Biçim:
Adobe Portable Document Format
Açıklama:
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Beslenme ve Diyetetik Bölümü Yayın Koleksiyonu
Artvin MYO Koleksiyonu Yayın Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu