Synthesis and characterization of metallophthalocyanine with morpholine containing Schiff base and determination of their antimicrobial and antioxidant activities
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Science SA
Erişim Hakkı
info:eu-repo/semantics/embargoedAccess
Özet
In this work, novel metallophthalocyanine compounds (M = Zn, Cu, Co) bearing four 2-methoxy-4-{(Z)-[(4-morpholin-4-ylphenyl) imino] methyl} phenol at the peripheral positions were sythesized starting from the new phthalonitrile derivative (2). These new compounds (2-5) have been characterized by a combination of FT-IR, H-1 NMR (for compounds 2 and 3), C-13 NMR (for compound 2), UV-Vis (for compounds 3,4 and 5) and mass spectrophotometry techniques. Antioxidant activities of the metallophthalocyanines were investigated by using DPPH free radical scavenging assay and FRAP (ferric ion reducing antioxidant power) method. The antimicrobial activity of the synthesized metallo phthalocyanine compounds (3-5) were determined against the selected different six standart bacteria isolates by microdilution broth assay with Alamar Blue Dye. Most affected bacteria from the compounds were standard E. coli and S. typhimurium (MIC 625 mu g/ml). Standart Y. enterocolitica and S. aureus have been less affected by the compounds (MIC 10.000 mu g/ml). (C) 2019 Published by Elsevier B.V.
Açıklama
Anahtar Kelimeler
Metallophthalocyanine, Antioxidation, Antimicrobial, Morpholine, Schiff base
Kaynak
Journal Of Organometallic Chemistry
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
900
Sayı
Künye
Unluer, D., Aktas Kamiloglu, A., Direkel, S., Bektas, E., Kantekin, H., & Sancak, K. (2019). Synthesis and characterization of metallophthalocyanine with morpholine containing Schiff base and determination of their antimicrobial and antioxidant activities. Journal of Organometallic Chemistry, 900. https://doi.org/10.1016/j.jorganchem.2019.120936
