An efficient microwave-assisted synthesis of novel quinolone-triazole and conazole-triazole hybrid derivatives as antimicrobial and anticancer agents
Yükleniyor...
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
1,2,4-Triazole-fluoroquinolone and 1,2,4-triazole–conazole hybrids aredesigned, synthesized, and investigated in vitro against a variety of commondiseases. The structure of the newly synthesized compounds are characterizedfrom spectral data (IR,1H NMR,13C NMR, and LC–MS). The antibacterialactivity against both Gram-positive and Gram-negative bacteria is shown to beenhanced by many of the produced compounds. Also, some of the productsare found to have strong antiproliferative effects aganist HeLa cervical cancercells, whilst demonstrating cytotoxic effects toward normal cells
Açıklama
Anahtar Kelimeler
Kaynak
Journal of Heterocyclic Chemistry
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
Sayı
Künye
Cebeci, Y. U., Ceylan, Ş., Karaoğlu, Ş. A., & Altun, M. (2022). An efficient microwave-assisted synthesis of novel quinolone-triazole and conazole-triazole hybrid derivatives as antimicrobial and anticancer agents. Journal of Heterocyclic Chemistry.
