An efficient microwave-assisted synthesis of novel quinolone-triazole and conazole-triazole hybrid derivatives as antimicrobial and anticancer agents

dc.contributor.authorUygun Cebeci, Yıldız
dc.contributor.authorCeylan, Şule
dc.contributor.authorAlpay Karaoğlu, Şengül
dc.contributor.authorAltun, Muhammed
dc.date.accessioned2022-09-28T13:06:12Z
dc.date.available2022-09-28T13:06:12Z
dc.date.issued2022
dc.departmentAÇÜ, Orman Fakültesi, Orman Mühendisliği Bölümüen_US
dc.description.abstract1,2,4-Triazole-fluoroquinolone and 1,2,4-triazole–conazole hybrids aredesigned, synthesized, and investigated in vitro against a variety of commondiseases. The structure of the newly synthesized compounds are characterizedfrom spectral data (IR,1H NMR,13C NMR, and LC–MS). The antibacterialactivity against both Gram-positive and Gram-negative bacteria is shown to beenhanced by many of the produced compounds. Also, some of the productsare found to have strong antiproliferative effects aganist HeLa cervical cancercells, whilst demonstrating cytotoxic effects toward normal cells
dc.identifier.citationCebeci, Y. U., Ceylan, Ş., Karaoğlu, Ş. A., & Altun, M. (2022). An efficient microwave-assisted synthesis of novel quinolone-triazole and conazole-triazole hybrid derivatives as antimicrobial and anticancer agents. Journal of Heterocyclic Chemistry.en_US
dc.identifier.doi10.1002/jhet.4560
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://hdl.handle.net/11494/4254
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorCeylan, Şule
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Heterocyclic Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleAn efficient microwave-assisted synthesis of novel quinolone-triazole and conazole-triazole hybrid derivatives as antimicrobial and anticancer agentsen_US
dc.typeArticle

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