Green synthesis of silver nanoparticles using Sambucus ebulus leaves extract: Characterization, quantitative analysis of bioactive molecules, antioxidant and antibacterial activities

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dc.contributor.authorKaran, Tunay
dc.contributor.authorGönülalan, Zafer
dc.contributor.authorErenler, Ramazan
dc.contributor.authorKölemen, Uğur
dc.contributor.authorEminağaoğlu, Özgür
dc.date.accessioned2024-12-03T13:04:20Z
dc.date.available2024-12-03T13:04:20Z
dc.date.issued2024
dc.departmentAÇÜ, Orman Fakültesi, Orman Mühendisliği Bölümüen_US
dc.description.abstractSambucus ebulus is a well-known medicinal plant used as a traditional medicine due to its bioactive compound contents. The importance of nanotechnology has increased recently since it has effective and widespread usage areas. In this study, silver nanoparticles (AgNPs@Se) were synthesized using S. ebulus leaf extract and their structures were clarified by spectroscopic analyses including FTIR, UV–Vis, and XRD. The morphology and particle size of AgNPs@Se were determined by SEM analysis. Quantitative analysis of bioactive compounds of S. ebulus leaf extract was defined by HPLC analysis. Antioxidant activity of extract and AgNPs@Se was executed by DPPH•, ABTS•+, and FRAP assays. The antibacterial activity of AgNPs was carried out using agar well diffusion and microdilution broth methods. Quantitative analysis of bioactive compounds in S. ebulus leaf extract was established by HPLC. The average particle size of nanoparticles was calculated as 18.6 nm. Isoquercitrin was found as a major product. AgNPs@Se displayed excellent antioxidant activity, but they revealed a moderate antibacterial effect. The structure of nanoparticles was assigned as a face center cubic unit cell. Hence, nanoparticles could be a favorable agent for the pharmaceutical and food industry.
dc.identifier.doi10.1016/j.molstruc.2023.136836
dc.identifier.issn0022-2860
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.molstruc.2023.136836
dc.identifier.urihttps://hdl.handle.net/11494/5097
dc.identifier.volume1296en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherElsevier B.V.en_US
dc.relation.ispartofJournal of Molecular Structure
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectAntibacterialen_US
dc.subjectAntioxidanten_US
dc.subjectHPLCen_US
dc.subjectSambucus Ebulusen_US
dc.subjectSilver Nanoparticleen_US
dc.titleGreen synthesis of silver nanoparticles using Sambucus ebulus leaves extract: Characterization, quantitative analysis of bioactive molecules, antioxidant and antibacterial activitiesen_US
dc.typeArticle

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