A modified Biginelli reaction toward oxygen-bridged tetrahydropyrimidines fused with substituted 1,2,4-triazole ring
Yükleniyor...
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A microwave-assisted Biginelli-like three-component condensation using salicylic aldehyde derivatives, acetone, and 5-substituted 3-amino-1,2,4-triazoles instead of the urea component results in the formation of oxygen-bridged tetrahydrotriazolopyrimidine derivatives (11,12-dihydro-5,11-methano[1,2,4]triazolo[1,5-c][1,3,5]benzoxadiazocines) in good yields and high purity. A plausible reaction mechanism for this transformation is discussed in details using literature and experimental data.
Açıklama
Anahtar Kelimeler
3-amino-1,2,4-triazole, Benzoxadiazocine, Oxygen-bridged structure, Biginelli reaction, Cascade reaction, Microwave-assisted synthesis, Multicomponent reaction, Reaction mechanism
Kaynak
Chemistry of Heterocyclic Compounds
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
53
Sayı
11
Künye
Gümüş, M. K., Gorobets, N. Y., Sedash, Y. V., Chebanov, V. A., & Desenko, S. M. (2017). A modified Biginelli reaction toward oxygen-bridged tetrahydropyrimidines fused with substituted 1,2,4-triazole ring. Chemistry of Heterocyclic Compounds, 1. https://doi.org/10.1007/s10593-018-2204-3
