A modified Biginelli reaction toward oxygen-bridged tetrahydropyrimidines fused with substituted 1,2,4-triazole ring

dc.authorid0000-0001-6373-5221en_US
dc.authorid0000-0001-8914-3232en_US
dc.authorid0000-0001-7564-778Xen_US
dc.contributor.authorGorobets, Nikolay Yu.
dc.contributor.authorSedash, Yuriy V.
dc.contributor.authorChebanov, Valentin A.
dc.contributor.authorDesenko, Sergey M.
dc.contributor.authorGümüş, Mustafa Kemal
dc.date.accessioned2020-03-04T11:13:21Z
dc.date.available2020-03-04T11:13:21Z
dc.date.issued2017
dc.departmentAÇÜ, Eğitim Fakültesien_US
dc.description.abstractA microwave-assisted Biginelli-like three-component condensation using salicylic aldehyde derivatives, acetone, and 5-substituted 3-amino-1,2,4-triazoles instead of the urea component results in the formation of oxygen-bridged tetrahydrotriazolopyrimidine derivatives (11,12-dihydro-5,11-methano[1,2,4]triazolo[1,5-c][1,3,5]benzoxadiazocines) in good yields and high purity. A plausible reaction mechanism for this transformation is discussed in details using literature and experimental data.
dc.description.sponsorshipArtvin Coruh University. BAP-2012.F19.02.24 Council of Higher Education of Turkey, Mevlana Exchange Program: MEV-2016-027en_US
dc.identifier.citationGümüş, M. K., Gorobets, N. Y., Sedash, Y. V., Chebanov, V. A., & Desenko, S. M. (2017). A modified Biginelli reaction toward oxygen-bridged tetrahydropyrimidines fused with substituted 1,2,4-triazole ring. Chemistry of Heterocyclic Compounds, 1. https://doi.org/10.1007/s10593-018-2204-3en_US
dc.identifier.doi10.1007/s10593-018-2204-3
dc.identifier.endpage1267en_US
dc.identifier.issue11en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage1261en_US
dc.identifier.urihttps://hdl.handle.net/11494/1995
dc.identifier.volume53en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorGümüş, Mustafa Kemal
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofChemistry of Heterocyclic Compounds
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject3-amino-1,2,4-triazoleen_US
dc.subjectBenzoxadiazocineen_US
dc.subjectOxygen-bridged structureen_US
dc.subjectBiginelli reactionen_US
dc.subjectCascade reactionen_US
dc.subjectMicrowave-assisted synthesisen_US
dc.subjectMulticomponent reactionen_US
dc.subjectReaction mechanismen_US
dc.titleA modified Biginelli reaction toward oxygen-bridged tetrahydropyrimidines fused with substituted 1,2,4-triazole ringen_US
dc.typeArticle

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