Antimicrobial activity and bioactive compound profile of extracts from tanacetum parthenium and salvia glutinosa naturally growing in Artvin province, Türkiye

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dc.contributor.authorAlbayrak İskender, Nurcan
dc.contributor.authorÇoban, Nurten
dc.date.accessioned2026-07-07T07:10:07Z
dc.date.available2026-07-07T07:10:07Z
dc.date.issued2025
dc.departmentAÇÜ, Sağlık Hizmetleri Meslek Yüksekokulu, Tıbbi Hizmetler ve Teknikler Bölümü
dc.description.abstractMedicinal and aromatic plants have gained prominence in pharmaceutical research due to the bioactive compounds they contain. The aim of this study is to determine the antimicrobial effects of methanol and ethanol extracts obtained from the aerial parts of Tanacetum parthenium and Salvia glutinosa plants, which naturally grow in the Artvin region, and to analyze the bioactive compounds present in these extracts. The antimicrobial activities of the extracts were evaluated by the disk diffusion method, and four bacterial strains Staphylococcus aureus (ATCC 25923), Enterococcus faecalis (ATCC 29212), Escherichia coli (ATCC 25922), Bacillus spizizenii (ATCC 6633), and the yeast Candida albicans (ATCC 10231) were used in the studies. The leaf extracts of T. parthenium showed activity against S. aureus, B. spizizenii, and E. faecalis, while the flower extracts exhibited antimicrobial activity only against S. aureus and B. spizizenii. The highest antimicrobial effect was observed in the leaf extract of S. glutinosa obtained with 96% ethanol, which was found to be more effective than the commercial antibiotic. Furthermore, HPLC analysis revealed that the main compound in both plant extracts was coumaric acid, and some phenolic compounds detected in these plants were reported for the first time in this study.
dc.identifier.doi10.7546/CRABS.2025.09.02
dc.identifier.endpage1294
dc.identifier.issn13101331
dc.identifier.issue9
dc.identifier.scopus2-s2.0-105029058731
dc.identifier.scopusqualityQ3
dc.identifier.startpage1285
dc.identifier.urihttps://hdl.handle.net/11494/6257
dc.identifier.volume78
dc.identifier.wosWOS:001585856000011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakScopus
dc.indekslendigikaynakWeb of Science
dc.institutionauthorAlbayrak İskender, Nurcan
dc.institutionauthorÇoban, Nurten
dc.language.isoen
dc.publisherAcademic Publishing House
dc.relation.ispartofComptes Rendus de L'Academie Bulgare des Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntimicrobial activity
dc.subjectBioactive compounds
dc.subjectHPLC analysis
dc.subjectPlant extracts
dc.subjectSalvia glutinosa
dc.subjectTanacetum parthenium
dc.titleAntimicrobial activity and bioactive compound profile of extracts from tanacetum parthenium and salvia glutinosa naturally growing in Artvin province, Türkiye
dc.typeArticle

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