First report of qnr and blaVIM-4-like producing clinical Alcaligenes faecalis isolated in Türkiye

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dc.authorid0000-0001-7175-5257
dc.authorid0000-0002-7757-6812
dc.authorid0000-0003-0267-8758
dc.authorid0000-0003-0737-9167
dc.authorid0000-0002-0535-943X
dc.authorid0000-0002-6301-611X
dc.contributor.authorAkyıldız, Esma
dc.contributor.authorSaral Sarıyer, Ayşegül
dc.contributor.authorKöse, Tuba
dc.contributor.authorArslan, Mikail
dc.contributor.authorBeriş, Fatih Şaban
dc.contributor.authorÖzad Düzgün, Azer
dc.date.accessioned2025-07-25T07:31:06Z
dc.date.available2025-07-25T07:31:06Z
dc.date.issued2023
dc.departmentAÇÜ, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü
dc.description.abstractThe study set out to look at the clinical strain of A. faecalis's antibiotic susceptibility pattern. Both biochemical and molecular approaches were used to identify A.faecalis. The VITEK compact system was used to analyze the strain's antibiotic susceptibility profile. The use of PCR was evaluated to determine the presence of resistance genes. It was also determined whether resistance determinants could be transferred. It was determined that A. feacalis showed resistance to imipenem, cefepime, ceftazidime, gentamicin, amikacin, netilmicin, tobramicin, ciprofloxacin, and levofloxacin. The blaVIM-4-like gene was present in this strain, according to the results of the PCR and DNA sequencing studies. In contrast to VIM-4, this blaVIM-4-like gene showed one amino acid change (Ala265Val).Filter-mating experiments showed that the blaVIM-4-like gene cannot be transferred from A. faecalis to E. coli. In this study, This research, demonstrated the presence of the blaVIM-4-like gene for the first time in A. faecalis from Turkey.
dc.identifier.doi10.17714/gumusfenbil.1179361
dc.identifier.endpage65
dc.identifier.issn2146538X
dc.identifier.issue1
dc.identifier.scopus2-s2.0-105004012757
dc.identifier.startpage57
dc.identifier.urihttps://hdl.handle.net/11494/5860
dc.identifier.volume13
dc.indekslendigikaynakScopus
dc.institutionauthorSaral Sarıyer, Ayşegül
dc.institutionauthorid0000-0002-7757-6812
dc.language.isoen
dc.publisherGumushane University
dc.relation.ispartofGumushane Universitesi Fen Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectA. faecalis
dc.subjectqnrB
dc.subjectVIM-4
dc.titleFirst report of qnr and blaVIM-4-like producing clinical Alcaligenes faecalis isolated in Türkiye
dc.title.alternativeTürkiye'den izole edilen qnr ve blaVIM-4-like üreten klinik Alcaligenes faecalis’in ilk raporu
dc.typeArticle

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