The kruppel-like factor (KLF) family, diseases, and physiological events

Basit Öğe Kaydı
dc.contributor.authorYüce, Kemal
dc.contributor.authorÖzkan, Ahmet İsmail
dc.date.accessioned2024-11-29T06:13:00Z
dc.date.available2024-11-29T06:13:00Z
dc.date.issued2024
dc.departmentAÇÜen_US
dc.description.abstractThe Kruppel-Like Factor family of regulatory proteins, which has 18 members, is transcription factors. This family contains zinc finger proteins, regulates the activation and suppression of transcription, and binds to DNA, RNA, and proteins. Klfs related to the immune system are Klf1, Klf2, Klf3, Klf4, Klf6, and Klf14. Klfs related to adipose tissue development and/or glucose metabolism are Klf3, Klf7, Klf9, Klf10, Klf11, Klf14, Klf15, and Klf16. Klfs related to cancer are Klf3, Klf4, Klf5, Klf6, Klf7, Klf8, Klf9, Klf10, Klf11, Klf12, Klf13, Klf14, Klf16, and Klf17. Klfs related to the cardiovascular system are Klf4, Klf5, Klf10, Klf13, Klf14, and Klf15. Klfs related to the nervous system are Klf4, Klf7, Klf8, and Klf9. Klfs are associated with diseases such as carcinogenesis, oxidative stress, diabetes, liver fibrosis, thalassemia, and the metabolic syndrome. The aim of this review is to provide information about the relationship of Klfs with some diseases and physiological events and to guide future studies.
dc.identifier.doi10.1016/j.gene.2023.148027
dc.identifier.issn0378-1119
dc.identifier.scopusqualityQ2
dc.identifier.urihttp://dx.doi.org/10.1016/j.gene.2023.148027
dc.identifier.urihttps://hdl.handle.net/11494/5052
dc.identifier.volume895en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier B.V.en_US
dc.relation.ispartofGene
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectCanceren_US
dc.subjectKlfsen_US
dc.subjectThe Cardiovascular Systemen_US
dc.subjectThe Immune Systemen_US
dc.subjectThe Nervous Systemen_US
dc.subjectTranscription Factorsen_US
dc.titleThe kruppel-like factor (KLF) family, diseases, and physiological eventsen_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
kemal.yuce-ahmetismail.ozkan.pdf
Boyut:
999.95 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Tıbbi-Aromatik Bitkiler Uygulama Ve Araştırma Merkezi
WoS İndeksli Yayınlar Koleksiyonu