In vitro Leishmanicidal and antimicrobial activity of fluorinated pyrazoline substituted silicon(IV), zinc(II), cobalt(II) and iron(II) metallophthalocyanines
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Dosyalar
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor and Francis Ltd.
Erişim Hakkı
info:eu-repo/semantics/embargoedAccess
Özet
In this work, in vitro antibacterial and Leishmanicidal activities of a ligand and phthalocyanine derivatives (2, 3, 3a–3c and 4) were tested for six selected standard bacteria and one Leishmania species. The synthesis of fluorinated pyrazoline compound (2) was first carried out from a chalcone precursor (1). Then, peripherally tetra-substituted metallophthalocyanines (zinc(II) (3a), cobalt(II) (3b) and iron(II) (3c)) and axially di-substituted silicon(IV) (4) containing fluorinated pyrazoline groups were obtained. The characterizations of 2, 3, 3a–3c and 4 were performed by IR,1H and 13C NMR, MALDI-TOF-MS and UV-Vis spectra and elemental analyses. The antibacterial and Leishmanicidal activities of the pyrazoline and phthalocyanine compounds were investigated.
Açıklama
Anahtar Kelimeler
Antimicrobial activity, Fluorinated pyrazoline, Leishmaniasis, Leishmanicidal activity, Metallo-phthalocyanine, Synthesis
Kaynak
Journal of Coordination Chemistry
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
76
Sayı
16-24
