In vitro Leishmanicidal and antimicrobial activity of fluorinated pyrazoline substituted silicon(IV), zinc(II), cobalt(II) and iron(II) metallophthalocyanines

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dc.contributor.authorAktaş Kamiloğlu, Ayşe
dc.contributor.authorDirekel, Şahin
dc.contributor.authorÇelik, Gonca
dc.date.accessioned2025-07-25T08:52:43Z
dc.date.available2025-07-25T08:52:43Z
dc.date.issued2023
dc.departmentAÇÜ, Artvin Meslek Yüksekokulu, Laboratuvar Teknolojisi Bölümü
dc.description.abstractIn this work, in vitro antibacterial and Leishmanicidal activities of a ligand and phthalocyanine derivatives (2, 3, 3a–3c and 4) were tested for six selected standard bacteria and one Leishmania species. The synthesis of fluorinated pyrazoline compound (2) was first carried out from a chalcone precursor (1). Then, peripherally tetra-substituted metallophthalocyanines (zinc(II) (3a), cobalt(II) (3b) and iron(II) (3c)) and axially di-substituted silicon(IV) (4) containing fluorinated pyrazoline groups were obtained. The characterizations of 2, 3, 3a–3c and 4 were performed by IR,1H and 13C NMR, MALDI-TOF-MS and UV-Vis spectra and elemental analyses. The antibacterial and Leishmanicidal activities of the pyrazoline and phthalocyanine compounds were investigated.
dc.identifier.doi10.1080/00958972.2023.2289359
dc.identifier.endpage2027
dc.identifier.issn00958972
dc.identifier.issue16-24
dc.identifier.scopus2-s2.0-85179746169
dc.identifier.scopusqualityQ3
dc.identifier.startpage2014
dc.identifier.urihttps://hdl.handle.net/11494/5873
dc.identifier.volume76
dc.indekslendigikaynakScopus
dc.institutionauthorAktaş Kamiloğlu, Ayşe
dc.language.isoen
dc.publisherTaylor and Francis Ltd.
dc.relation.ispartofJournal of Coordination Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectAntimicrobial activity
dc.subjectFluorinated pyrazoline
dc.subjectLeishmaniasis
dc.subjectLeishmanicidal activity
dc.subjectMetallo-phthalocyanine
dc.subjectSynthesis
dc.titleIn vitro Leishmanicidal and antimicrobial activity of fluorinated pyrazoline substituted silicon(IV), zinc(II), cobalt(II) and iron(II) metallophthalocyanines
dc.typeArticle

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