RhoA/ROCK-1 signaling pathway and oxidative stress in coronary artery disease patients

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dc.authorid0000-0002-2223-1331en_US
dc.authorid0000-0002-8063-4972en_US
dc.contributor.authorDokumacıoğlu, Eda
dc.contributor.authorDüzcan, İbrahim
dc.contributor.authorİskender, Hatice
dc.contributor.authorŞahin, Arzu
dc.date.accessioned2021-08-09T08:45:23Z
dc.date.available2021-08-09T08:45:23Z
dc.date.issued2021
dc.departmentAÇÜ, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümüen_US
dc.description.abstractObjective: The aim of this clinical study is to determine the depression and anxiety levels in coronary artery bypass graft (CABG) surgery patients in the pre and postoperative periods. Methods: This clinical prospective study was done with 65 patients. Beck's Depression Inventory (BDI) and Beck's Anxiety Inventory (BAI) tests were performed in patients who had a diagnosis of coronary artery disease and were awaiting CABG surgery. These patients presented characteristic symptoms of anxiety and depression and BDI and BAI tests are important to assess these symptoms. Results: We found out that depression and anxiety levels were higher in the postoperative than in the preoperative period (P<0.001). Both anxiety and depression levels were increased significantly following CABG operation when compared with preoperative levels in all patients. Statistical correlation of depression and anxiety in different ages, genders, and professions were evaluated too, but we did not found a correlation between them (P>0.05). Conclusion: We suggest that good management of the psychological condition of cardiac surgery candidates, as well as post-bypass patients, will improve quality of life and cardiovascular outcomes in these patients.
dc.identifier.citationDokumacıoğlu, E., Düzcan, İ., İskender, H., & Şahin, A. RhoA/ROCK-1 Signaling Pathway and Oxidative Stress in Coronary Artery Disease Patients. Brazilian journal of cardiovascular surgery.en_US
dc.identifier.doi10.21470/1678-9741-2020-0525
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://hdl.handle.net/11494/3315
dc.identifier.volumeArticle in presen_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorDokumacıoğlu, Eda
dc.institutionauthorİskender, Hatice
dc.language.isoenen_US
dc.publisherSciELO - Brazilen_US
dc.relation.ispartofBrazilian journal of cardiovascular surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnxiety Disordersen_US
dc.subjectCoronary Artery Bypassen_US
dc.subjectCoronary Artery Diseasesen_US
dc.subjectDepressive Disorderen_US
dc.subjectQuality of Lifeen_US
dc.titleRhoA/ROCK-1 signaling pathway and oxidative stress in coronary artery disease patientsen_US
dc.typeArticle

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