Carvacrol partially reverses symptoms of diabetes in STZ-induced diabetic rats

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dc.authorid0000-0001-8567-807Xen_US
dc.authorid0000-0001-9658-3316en_US
dc.contributor.authorBayramoğlu, Gökhan
dc.contributor.authorŞentürk, Hakan
dc.contributor.authorBayramoğlu, Ayşegül
dc.contributor.authorUyanoğlu, Mustafa
dc.contributor.authorÇolak, Suat
dc.contributor.authorÖzmen, Ayşe
dc.contributor.authorKolankaya, Durdane
dc.date.accessioned2020-11-09T10:57:18Z
dc.date.available2020-11-09T10:57:18Z
dc.date.issued2014
dc.departmentAÇÜ, Artvin Meslek Yüksekokuluen_US
dc.description.abstractLittle is known about the protective effects of carvacrol on the symptoms of streptozotocin induced diabetes in rats. Hence, this present study was designed to evaluate the protective effect of the strong antioxidant, carvacrol, on the symptoms of streptozotocin induced diabetes in rats. Carvacrol at the doses of 25 and 50 mg/kg body weight were orally administered to diabetic rats for a period of 7 days after the onset of diabetes. Food-water intake and body weight changes were daily recorded. Biochemical parameters such as serum glucose, insulin, total cholesterol, alanine aminotransferase, aspartate aminotransferase and lactate dehydrogenase were measured. Although treatment of diabetic rats with oral administration of carvacrol resulted in a slight reduction in serum glucose level and significant reduction in serum total cholesterol, alanine aminotransferase, aspartate aminotransferase and lactate dehydrogenase in comparison with diabetic control rats, there were no significant differences in serum insulin levels, foodwater intake values and body weight changes. Despite the inadequacy of carvacrol on diabetes treatments, it was determined to have at least a partially protective role on liver enzymes.
dc.description.sponsorshipArtvin Coruh University: 2011.F15.02.19en_US
dc.identifier.citationBayramoğlu, G., Şentürk, H., Bayramoğlu, A., Uyanoğlu, M., Çolak, S., Özmen, A., & Kolankaya, D. (2014). Carvacrol partially reverses symptoms of diabetes in STZ-induced diabetic rats. Cytotechnology, 66(2), 251-257.en_US
dc.identifier.doi10.1007/s10616-013-9563-5
dc.identifier.endpage257en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage251en_US
dc.identifier.urihttps://hdl.handle.net/11494/2432
dc.identifier.volume66en_US
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorBayramoğlu, Ayşegül
dc.institutionauthorÇolak, Suat
dc.institutionauthorBayramoğlu, Gökhan
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofCytotechnology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCarvacrolen_US
dc.subjectDiabetesen_US
dc.subjectStreptozotocinen_US
dc.subjectRaten_US
dc.subjectLiveren_US
dc.titleCarvacrol partially reverses symptoms of diabetes in STZ-induced diabetic ratsen_US
dc.typeArticle

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