Effect of oleanolic acid administration on hepatic AMPK, SIRT-1, IL-6 and NF-κB levels in experimental diabetes

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dc.authoridHatice İskender / 0000-0002-8063-4972en_US
dc.authoridEda Dokumacıoğlu / 0000-0002-2223-1331en_US
dc.contributor.authorİskender, Hatice
dc.contributor.authorDokumacıoğlu, Eda
dc.contributor.authorTerim Kapakin, Kübra Asena
dc.contributor.authorBolat, İsmail
dc.contributor.authorMokhtare, Behzat
dc.contributor.authorHayırlı, Armağan
dc.contributor.authorYenice, Güler
dc.date.accessioned2023-02-20T12:57:22Z
dc.date.available2023-02-20T12:57:22Z
dc.date.issued2023
dc.departmentAÇÜ, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümüen_US
dc.description.abstractDiabetes mellitus (DM) is an important public health problem all over the world, considering its complications and increasing prevalence. Oleanolic acid (OA) has anti-diabetic property via modulating glucose metabolism and acting as 5?–adenosine monophosphate (AMP)–activated protein kinase (AMPK) / Sirtuin–1 (SIRT–1) activator and Interleukin 6 (IL–6) / Nuclear factor kappa B (NF–?B) inhibitor. This research questioned if the OA treatment amliorates the hepatic inflammatory profile in the diabetic rats
dc.identifier.citationİskender, H., Dokumacıoğlu, E., Terim Kapakin, K. A., Bolat, I., Mokhtare, B., Hayırlı, A., & Yenice, G. (2023). Effect of Oleanolic acid administration on hepatic AMPK, SIRT-1, IL-6 and NF-κB levels in experimental diabetes. Journal of Diabetes & Metabolic Disorders. ‌en_US
dc.identifier.doi10.1007/s40200-022-01178-x
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://doi.org/10.1007/s40200-022-01178-x
dc.identifier.urihttps://hdl.handle.net/11494/4714
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorİskender, Hatice
dc.institutionauthorDokumacıoğlu, Eda
dc.language.isoenen_US
dc.publisherSpringer Linken_US
dc.relation.ispartofJournal of Diabetes & Metabolic Disorders
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAMPKen_US
dc.subjectDiabetesen_US
dc.subjectInflammationen_US
dc.subjectOleanolic aciden_US
dc.subjectSIRT-1en_US
dc.titleEffect of oleanolic acid administration on hepatic AMPK, SIRT-1, IL-6 and NF-κB levels in experimental diabetesen_US
dc.typeArticle

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