Effects of serum uric acid levels on the arginase pathway in women with metabolic syndrome

Basit Öğe Kaydı
dc.contributor.authorUslu, Sema
dc.contributor.authorÖzçelik, Eda
dc.contributor.authorKebapçı, Nur
dc.contributor.authorTemel, Halide Edip
dc.contributor.authorDemirci, Fatih
dc.contributor.authorErgün, Bülent
dc.contributor.authorDemirüstü, Canan
dc.date.accessioned2020-11-13T07:18:19Z
dc.date.available2020-11-13T07:18:19Z
dc.date.issued2016
dc.departmentAÇÜ, Sağlık Bilimleri Fakültesien_US
dc.description.abstractAbstract Background Elevated serum uric acid levels and increased arginase activity are risk factors for cardiovascular diseases (CVD). The aim of the present study was to investigate effects of serum uric acid levels on the arginase pathway in women with metabolic syndrome (MetS). Methods Serum arginase activity, and nitrite and uric acid levels were measured in 48 women with MetS and in 20 healthy controls. The correlation of these parameters with components of MetS was also evaluated. Results Our data show statistically higher arginase activity and uric acid levels but lower nitrite levels in women with MetS compared to controls. Serum uric acid levels were negatively correlated with HDL cholesterol, nitrite levels and positively with Body Mass Index, waist to hip ratio, triglyceride and total cholesterol levels, systolic blood pressure, Homeostasis Model Assessment-Insulin Resistance-Index, serum arginase activity, and LDL-cholesterol levels in women with MetS. Conclusion Results of the present study suggest that serum uric acid levels may contribute to the pathogenesis of MetS through a process mediated by arginase pathway, and serum arginase activity and nitrite and uric acid levels can be used as indicators of CVD in women with MetS.
dc.identifier.citationUslu, S., Özçelik, E., Kebapçı, N., Temel, H. E., Demirci, F., Ergün, B., & Demirüstü, C. (2016). Effects of serum uric acid levels on the arginase pathway in women with metabolic syndrome. Irish Journal of Medical Science. 185(1), 259-263.en_US
dc.identifier.doi10.1007/s11845-015-1347-9
dc.identifier.endpage263en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityN/A
dc.identifier.startpage259en_US
dc.identifier.urihttps://hdl.handle.net/11494/2452
dc.identifier.volume185en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzçelik, Eda
dc.language.isoenen_US
dc.publisherSpringer London LTDen_US
dc.relation.ispartofIrish Journal of Medical Science.
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArginase pathwayen_US
dc.subjectMetabolic syndromeen_US
dc.subjectSerum uric acid levelsen_US
dc.titleEffects of serum uric acid levels on the arginase pathway in women with metabolic syndromeen_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
sema.uslu.pdf
Boyut:
435.11 KB
Biçim:
Adobe Portable Document Format
Açıklama:
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Beslenme ve Diyetetik Bölümü Yayın Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu